Bmpr1b (NM_001277220) Mouse Tagged ORF Clone

CAT#: MR230201

Bmpr1b (myc-DDK-tagged) - Mouse bone morphogenetic protein receptor, type 1B (Bmpr1b), transcript variant 5

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Bmpr1b
• Synonyms: Acvrlk6; AI385617; ALK-6; Alk6; AV355320; BMPR-1B; BMPR-IB; CFK-43a; SKR6
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MR230201 representing NM_001277220
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGTGGGCACCAAGAAGGAGGATGGAGAGAGTACAGCCCCCACCCCTCGGCCCAAGATCCTACGTTGTAA
  ATGCCACCACCACTGTCCGGAAGACTCAGTCAACAATATCTGCAGATGGGTACTGCTTCACGATGATAGA
  AGAAGATGACTCTGGAATGCCTGTTGTCACCTCTGGATGTCTAGGACTAGAAGGGTCAGATTTTCAATGT
  CGTGACACTCCCATTCCTCATCAAAGAAGATCAATTGAATGCTGCACAGAAAGGAATGAGTGTAATAAAG
  ACCTCCACCCCACTCTGCCTCCTCTCAAGGACAGAGATTTTGTTGATGGGCCCATACACCACAAGGCCTT
  GCTTATCTCTGTGACTGTCTGTAGTTTACTCTTGGTCCTCATTATTTTATTCTGTTACTTCAGGTATAAA
  AGACAAGAAGCCCGACCTCGGTACAGCATTGGGCTGGAGCAGGACGAGACATACATTCCTCCTGGAGAGT
  CCCTGAGAGACTTGATCGAGCAGTCTCAGAGCTCGGGAAGTGGATCAGGCCTCCCTCTGCTGGTCCAAAG
  GACAATAGCTAAGCAAATTCAGATGGTGAAGCAGATTGGAAAAGGCCGCTATGGCGAGGTGTGGATGGGA
  AAGTGGCGTGGAGAAAAGGTGGCTGTGAAAGTGTTCTTCACCACGGAGGAAGCCAGCTGGTTCCGAGAGA
  CTGAGATATATCAGACGGTCCTGATGCGGCATGAGAATATTCTGGGGTTCATTGCTGCAGATATCAAAGG
  GACTGGGTCCTGGACTCAGTTGTACCTCATCACAGACTATCATGAAAACGGCTCCCTTTATGACTATCTG
  AAATCCACCACCTTAGACGCAAAGTCCATGCTGAAGCTAGCCTACTCCTCTGTCAGCGGCCTATGCCATT
  TACACACGGAAATCTTTAGCACTCAAGGCAAGCCAGCAATCGCCCATCGAGACTTGAAAAGTAAAAACAT
  CCTGGTGAAGAAAAATGGAACTTGCTGCATAGCAGACCTGGGCTTGGCTGTCAAGTTCATTAGTGACACA
  AATGAGGTTGACATCCCACCCAACACCCGGGTTGGCACCAAGCGCTATATGCCTCCAGAAGTGCTGGACG
  AGAGCTTGAATAGAAACCATTTCCAGTCCTACATTATGGCTGACATGTACAGCTTTGGACTCATCCTCTG
  GGAGATTGCAAGGAGATGTGTTTCTGGAGGTATAGTGGAAGAATACCAGCTTCCCTATCACGACCTGGTG
  CCCAGTGACCCTTCTTATGAGGACATGAGAGAAATTGTGTGCATGAAGAAGTTACGGCCTTCATTCCCCA
  ATCGATGGAGCAGTGATGAGTGTCTCAGGCAGATGGGGAAGCTTATGACAGAGTGCTGGGCGCAGAATCC
  TGCCTCCAGGCTGACGGCCCTGAGAGTTAAGAAAACCCTTGCCAAAATGTCAGAGTCCCAGGACATTAAA
  CTC
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >MR230201 representing NM_001277220
  Red=Cloning site Green=Tags(s)
  
  MWAPRRRMERVQPPPLGPRSYVVNATTTVRKTQSTISADGYCFTMIEEDDSGMPVVTSGCLGLEGSDFQC
  RDTPIPHQRRSIECCTERNECNKDLHPTLPPLKDRDFVDGPIHHKALLISVTVCSLLLVLIILFCYFRYK
  RQEARPRYSIGLEQDETYIPPGESLRDLIEQSQSSGSGSGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMG
  KWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYL
  KSTTLDAKSMLKLAYSSVSGLCHLHTEIFSTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISDT
  NEVDIPPNTRVGTKRYMPPEVLDESLNRNHFQSYIMADMYSFGLILWEIARRCVSGGIVEEYQLPYHDLV
  PSDPSYEDMREIVCMKKLRPSFPNRWSSDECLRQMGKLMTECWAQNPASRLTALRVKKTLAKMSESQDIK
  L
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001277220
• ORF Size: 1473 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001277220.1, NP_001264149.1
• RefSeq Size: 5357
• RefSeq ORF: 1476
• Locus ID: 12167
• MW: 56.3 kDa
• Gene Summary: This gene encodes a serine/threonine kinase that functions as a receptor for bone morphogenetic proteins (BMPs). The encoded protein is a type I receptor, and forms a complex of two type II and two type I receptors at the cell membrane. This complex signals downstream to activate SMAD transcriptional regulators. This signaling is important in skeletal and bone development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]