Arntl2 (NM_001289680) Mouse Tagged ORF Clone

CAT#: MR230548

Arntl2 (myc-DDK-tagged) - Mouse aryl hydrocarbon receptor nuclear translocator-like 2 (Arntl2), transcript variant 3

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Arntl2
• Synonyms: 4632430A05Rik; bHLHe6; BMAL2; CLIF; MOP9
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MR230548 representing NM_001289680
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGAGTTTCCAAGGAAACGCAGAGGCAGAGATTCCCAGCCACTCCAGTCAGAATTCATGACAGACACAA
  CAGTGGAAAGTCTTCCCCAGAATCCCTTTGCCTCTCTTCTTTCAACAAGAACAGGAGTATCAGCGCCCAG
  TGGCATCAGGGAAGCTCACAGCCAGATGGAAAAGCGTCGGAGAGACAAGATGAACCATCTGATTCAGAAA
  CTGTCATCTATGATCCCTCCACACATCCCCACGGCCCACAAACTGGACAAGCTCAGCGTCTTGAGGAGGG
  CGGTGCAGTACTTGAGGTCTCTGAGAGGCATGACAGAGCTTTACTTAGGAGAAAACTCTAAACCTTCATT
  TATTCAGGATAAGGAACTCAGTCACTTAATCCTCAAGGCAGCAGAAGGCTTCCTGTTTGTGGTTGGATGC
  GAAAGAGGGAGAATTTTTTACGTTTCTAAGTCTGTCTCCAAAACACTGCGTTATGATCAGGCTAGCTTGA
  TAGGACAGAATTTGTTTGACTTCTTACACCCAAAAGACGTCGCCAAAGTAAAGGAACAACTTTCTTGTGA
  TGGTTCACCAAGAGAGAAACCTATAGACACCAAAACCTCTCAGGTTTACAGTCACCCCTACACTGGGCGA
  CCACGCATGCATTCTGGCTCCAGACGATCTTTCTTCTTTAGAATGAAGAGCTGTACCGTCCCTGTCAAAG
  AAGAGCAGCCATGCTCGTCCTGCTCAAAGAAGAAAGACCATAGAAAATTCCACACCGTCCATTGCACTGG
  ATACTTGAGAAGCTGGCCTCTGAATGTTGTTGGCATGGAGAAAGAGTCGGGTGGTGGGAAGGACAGCGGT
  CCTCTTACCTGCCTTGTGGCTATGGGACGGTTGCATCCATACATTGTCCCTCAAAAGAGTGGCAAGATCA
  ACGTGAGACCGGCTGAGTTCATAACTCGCTTCGCAATGAACGGGAAATTCGTCTATGTTGACCAAAGGGC
  AACGGCAATTTTAGGATACCTGCCTCAGGAACTTTTGGGAACTTCATGTTATGAATATTTTCATCAGGAT
  GACCACAGTAGTTTGACTGACAAGCACAAAGCAGTTCTGCAGAGTAAGGAGAAAATACTTACAGACTCAT
  ACAAATTCAGAGTGAAGGATGGTGCCTTCGTGACTCTGAAGAGTGAGTGGTTCAGCTTCACAAACCCTTG
  GACCAAAGAGCTGGAGTACATTGTGTCTGTCAACACATTGGTTTTGGGGCGCAGTGAGACCAGGCTGTCT
  TTGCTTCATTGCGGCGGCAGCAGCCAGTCCTCCGAAGACTCATTTAGACAATCCTGCATCAATGTGCCCG
  GTGTATCCACGGGGACCGTCCTTGGTGCTGGGAGTATTGGAACAGATATTGCAAATGAGGTTCTGAGTTT
  ACAGAGATTACACTCTTCATCCCCAGAAGATGCAAGCCCTTCAGAAGAAGTGAGAGATGACTGCAGTGCA
  TCCACTAGGGAGCCTTTTGCAGTGAGCCCTTCTGAAACAGAGGTCCTGGAGGCTGCCAGGCAACACCAGA
  GCACTGAACCCGCCCACCCTCACGGACCACTTCCCGGTGACAGTGCCCAGCTGGGTTTTGATGTCCTGTG
  TGACAGTGACAGCATAGACATGGCTGCATTCATGAATTACCTCGAAGCAGAGGGGGGCCTGGGTGACCCT
  GGGGACTTCAGTGACATCCAGTGGGCACTC
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >MR230548 representing NM_001289680
  Red=Cloning site Green=Tags(s)
  
  MEFPRKRRGRDSQPLQSEFMTDTTVESLPQNPFASLLSTRTGVSAPSGIREAHSQMEKRRRDKMNHLIQK
  LSSMIPPHIPTAHKLDKLSVLRRAVQYLRSLRGMTELYLGENSKPSFIQDKELSHLILKAAEGFLFVVGC
  ERGRIFYVSKSVSKTLRYDQASLIGQNLFDFLHPKDVAKVKEQLSCDGSPREKPIDTKTSQVYSHPYTGR
  PRMHSGSRRSFFFRMKSCTVPVKEEQPCSSCSKKKDHRKFHTVHCTGYLRSWPLNVVGMEKESGGGKDSG
  PLTCLVAMGRLHPYIVPQKSGKINVRPAEFITRFAMNGKFVYVDQRATAILGYLPQELLGTSCYEYFHQD
  DHSSLTDKHKAVLQSKEKILTDSYKFRVKDGAFVTLKSEWFSFTNPWTKELEYIVSVNTLVLGRSETRLS
  LLHCGGSSQSSEDSFRQSCINVPGVSTGTVLGAGSIGTDIANEVLSLQRLHSSSPEDASPSEEVRDDCSA
  STREPFAVSPSETEVLEAARQHQSTEPAHPHGPLPGDSAQLGFDVLCDSDSIDMAAFMNYLEAEGGLGDP
  GDFSDIQWAL
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001289680
• ORF Size: 1710 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001289680.1, NP_001276609.1
• RefSeq Size: 2596
• RefSeq ORF: 1713
• Locus ID: 272322
• MW: 64 kDa
• Gene Summary: This gene encodes a basic helix-loop-helix transcription factor belonging to the PAS (Per, Arnt, Sim) superfamily. The PAS proteins play important roles in adaptation to low atmospheric and cellular oxygen levels, exposure to certain environmental pollutants, and diurnal oscillations in light and temperature. This protein forms a transcriptionally active heterodimer with the circadian Clock protein, the structurally related Mop4, and hypoxia-inducible factors, such as Hif1alpha. Consistent with its role as a biologically relevant partner of circadian and hypoxia factors, this protein is coexpressed in regions of the brain such as the thalamus, hypothalamus, and amygdala. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2014]