Mpl (NM_001285496) Mouse Tagged ORF Clone

CAT#: MR230555

Mpl (myc-DDK-tagged) - Mouse myeloproliferative leukemia virus oncogene (Mpl), transcript variant 3

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Mpl
• Synonyms: c-mpl; CD110; hlb219; TPO-R
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MR230555 representing NM_001285496
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCCCTCTTGGGCCCTCTTCATGGTCACCTCCTGCCTCCTCTTGGCCCTTCCAAACCAGGCACAAGTCA
  CCAGCCAAGATGTCTTCTTGCTGGCCTTGGGCACAGAGCCCCTGAACTGCTTCTCCCAAACATTTGAGGA
  CCTCACCTGCTTCTGGGATGAGGAAGAGGCAGCACCCAGTGGGACATACCAGCTGCTGTATGCCTACCGA
  GGAGAGAAGCCCCGTGCATGCCCCCTGTATTCCCAGAGTGTGCCCACCTTTGGAACCCGGTATGTGTGCC
  AGTTTCCAGCCCAGGATGAAGTGCGCCTCTTCTTTCCGCTGCACCTCTGGGTGAAGAATGTGTCCCTCAA
  CCAGACTTTGATCCAGCGGGTGCTGTTTGTGGATAGTGTGGAAACCTGCTGCCCCACTTTGTGGATGCCG
  AACCCAGTCCCTGTTCTTGACCAGCCTCCGTGTGTTCATCCGACAGCATCCCAACCGCATGGACCAGTGA
  GGACCTCCCCAGCTGGAGAAGCTCCATTTCTGACAGTGAAGGGTGGAAGCTGTCTCGTCTCAGGCCTCCA
  GGCTGGCAAATCCTACTGGCTCCAGCTACGCAGCCAACCCGACGGGGTCTCCCTTCGTGGCTCCTGGGGA
  CCCTGGTCCTTCCCTGTGACTGTGGATCTTCCAGGAGATGCAGTGACAATTGGACTTCAGTGCTTTACCT
  TGGATCTGAAGATGGTCACCTGCCAGTGGCAGCAACAAGACCGCACTAGCTCCCAAGGCTTCTTCCGCCA
  CAGCAGGACGAGGTGCTGCCCCACAGACAGGGACCCCACCTGGGAGAAATGTGAAGAGGAGGAACCGCGT
  CCAGGATCACAGCCCGCTCTCGTCTCCCGCTGCCACTTCAAGTCACGAAATGACAGTGTTATTCACATCC
  TTGTAGAGGTGACCACAGCGCAAGGTGCCGTTCACAGCTACCTGGGCTCCCCTTTTTGGATCCACCAGGC
  TGTGCTCCTTCCCACCCCGAGCCTGCACTGGAGGGAGGTCTCAAGTGGAAGGCTGGAGTTGGAGTGGCAG
  CACCAGTCATCTTGGGCAGCTCAAGAGACCTGCTACCAGCTCCGGTACACGGGAGAAGGCCGTGAGGACT
  GGAAGGTGCTGGAGCCATCTCTCGGTGCCCGGGGAGGGACCCTAGAGCTGCGCCCCCGAGCTCGCTACAG
  CTTGCAGCTGCGTGCCAGGCTCAACGGCCCCACCTACCAAGGTCCCTGGAGCGCCTGGTCTCCCCCAGCT
  AGGGTGTCCACGGGCTCCGAGACTGCTTGGATCACCTTGGTGACTGCTCTGCTCCTGGTGCTGAGCCTCA
  GTGCCCTTCTGGGCCTACTGCTGCTAAAGTGGCAATTTCCTGCGCACTACAGGAGACTGAGGCATGCTTT
  GTGGCCCTCGCTTCCAGACCTACACCGGGTCCTAGGCCAGTACCTCAGAGACACTGCAGCCCTAAGTCCT
  TCTAAGGCCACGGTTACCGATAGCTGTGAAGAAGTGGAACCCAGCCTCCTGGAAATCCTCCCTAAGTCCT
  CAGAGAGCACTCCTTTACCTCTGTGTCCCTCCCAACCTCAGATGGACTACAGAGGACTGCAACCTTGCCT
  GCGGACCATGCCCCTGTCTGTGTGTCCACCCATGGCTGAGACGGGGTCCTGCTGCACCACACACATTGCC
  AACCACTCCTACCTACCACTAAGCTATTGGCAGCAGCCC
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >MR230555 representing NM_001285496
  Red=Cloning site Green=Tags(s)
  
  MPSWALFMVTSCLLLALPNQAQVTSQDVFLLALGTEPLNCFSQTFEDLTCFWDEEEAAPSGTYQLLYAYR
  GEKPRACPLYSQSVPTFGTRYVCQFPAQDEVRLFFPLHLWVKNVSLNQTLIQRVLFVDSVETCCPTLWMP
  NPVPVLDQPPCVHPTASQPHGPVRTSPAGEAPFLTVKGGSCLVSGLQAGKSYWLQLRSQPDGVSLRGSWG
  PWSFPVTVDLPGDAVTIGLQCFTLDLKMVTCQWQQQDRTSSQGFFRHSRTRCCPTDRDPTWEKCEEEEPR
  PGSQPALVSRCHFKSRNDSVIHILVEVTTAQGAVHSYLGSPFWIHQAVLLPTPSLHWREVSSGRLELEWQ
  HQSSWAAQETCYQLRYTGEGREDWKVLEPSLGARGGTLELRPRARYSLQLRARLNGPTYQGPWSAWSPPA
  RVSTGSETAWITLVTALLLVLSLSALLGLLLLKWQFPAHYRRLRHALWPSLPDLHRVLGQYLRDTAALSP
  SKATVTDSCEEVEPSLLEILPKSSESTPLPLCPSQPQMDYRGLQPCLRTMPLSVCPPMAETGSCCTTHIA
  NHSYLPLSYWQQP
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001285496
• ORF Size: 1719 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001285496.1, NP_001272425.1
• RefSeq Size: 2778
• RefSeq ORF: 1722
• Locus ID: 17480
• MW: 64.6 kDa
• Gene Summary: Receptor for thrombopoietin. May represent a regulatory molecule specific for TPO-R-dependent immune responses. [UniProtKB/Swiss-Prot Function]