Adam19 (NM_001291891) Mouse Tagged ORF Clone

CAT#: MR230652

Adam19 (myc-DDK-tagged) - Mouse a disintegrin and metallopeptidase domain 19 (meltrin beta) (Adam19), transcript variant 3

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Adam19
• Synonyms: AL024287; MADDAM; Mltnb; MTLNB
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MR230652 representing NM_001291891
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCCATGTGCTCCGTGTACCAGTCTGGAGGAGTTAGCATGGACCACTCCGAGAATGCCATTGGTGTAG
  CCTCCACTGTGGCCCATGAGATTGGCCACAACTTTGGCATGAGCCATGATTCTGCACACTGCTGTTCTGC
  CAGTGCAGCCGATGGCGGCTGCATCATGGCCGCCGCCACCGGGCACCCTTTCCCCAAAGTGTTCAGTTGG
  TGTAACAGGAAGGAGCTGGACAGGTATCTGCAGACAGGAGGAGGGATGTGTCTCTCCAACATGCCGGACA
  CTAGGACGCTGTATGGAGGCCGGAGGTGTGGCAACGGGTACCTGGAAGACGGTGAAGAATGTGACTGTGG
  AGAAGAGGAGGAATGTAAGAACCCTTGCTGCAATGCCTCCAACTGCACTCTGAAGGAAGGGGCAGAGTGT
  GCCCATGGTTCCTGCTGCCACCAGTGCAAGCTGGTGGCTCCTGGAACCCAGTGTCGGGAGCAGGTTCGGC
  AATGTGACCTCCCCGAGTTCTGCACCGGCAAGTCTCCCCACTGCCCCACCAACTATTATCAGATGGATGG
  CACCCCCTGCGAGGGTGGCCAGGCCTACTGCTACAACGGCATGTGCCTCACTTACCAGGAACAGTGCCAG
  CAGCTGTGGGGACCTGGAGCCCGGCCTGCCCTCGATCTTTGCTTTGAGAGGGTGAATGCTGCTGGTGACA
  CCTATGGAAACTGTGGCAAGGGCTTGAATGGCCAATACAGGAAGTGCAGTCCCAGGGATGCCAAGTGTGG
  GAAGATTCAGTGCCAGAGCACCCAGGCCCGGCCCCTGGAATCCAACGCAGTATCTATTGACACCACCATC
  ACCTTGAACGGGAGGCGGATCCACTGTCGGGGCACCCACGTCTACCGGGGTCCTGAGGAGGAGGAAGGGG
  AAGGTGACATGCTGGACCCAGGGCTGGTGATGACTGGAACCAAGTGTGGCCACAACCATATTTGCTTCGA
  GGGGCAGTGCAGGAACACCTCCTTCTTTGAGACGGAAGGCTGTGGGAAAAAGTGCAATGGCCACGGGGTC
  TGCAACAACAACAAGAACTGTCATTGCTTCCCTGGCTGGTCTCCACCTTTCTGTAACACCCCGGGAGATG
  GTGGCAGCGTCGACAGTGGTCCTTTGCCCCCTAAGAGTGTGGGTCCCGTGATCGCTGGGGTGTTTTCAGC
  TCTCTTCGTGTTGGCAGTTCTGGTGCTACTGTGTCACTGCTACAGACAGAGCCACAAACTGGGCAAACCC
  TCGGCTCTCCCTTTCAAGCTGCGGCATCAGTTCAGTTGTCCCTTCAGGGTATCTCAGAGTGGTGGAACTG
  GCCATGCCAACCCAACTTTCAAGTTGCAGACCCCCCAGGGCAAGCGAAAGGTGACTAACACCCCTGAATC
  CCTCCGGAAGCCGTCCCACCCCCCTCCCCGGCCCCCTCCAGACTACCTGCGCGTTGAATCGCCACCTGCA
  CCATTGCCGGCACATCTGAACAGGGCTGCTGGGAGCTCCCCAGAAGCTGGGGCTCGAATAGAAAGAAAGG
  AGTCAGCCAGGAGGCCTCCCCCAAGCCGACCCATGCCCCCTGCACCTAACTGCCTACTGTCCCAGGACTT
  CTCCAGGCCTCGACCACCTCAGAAGGCACTCCCAGCCAATCCGGTGCCAGGCCAAAGGACCGGTCCCAGG
  TCAGGAGGCACCTCCCTGCTTCAGCCCCCTACTTCTGGTCCTCAGCCCCCCAGGCCTCCAGCAGTGCCTG
  TTCCAAAGCTACCCGAGTACCGATCACAGAGGGTTGGAGCAATAATTAGCTCCAAGATC
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >MR230652 representing NM_001291891
  Red=Cloning site Green=Tags(s)
  
  MAMCSVYQSGGVSMDHSENAIGVASTVAHEIGHNFGMSHDSAHCCSASAADGGCIMAAATGHPFPKVFSW
  CNRKELDRYLQTGGGMCLSNMPDTRTLYGGRRCGNGYLEDGEECDCGEEEECKNPCCNASNCTLKEGAEC
  AHGSCCHQCKLVAPGTQCREQVRQCDLPEFCTGKSPHCPTNYYQMDGTPCEGGQAYCYNGMCLTYQEQCQ
  QLWGPGARPALDLCFERVNAAGDTYGNCGKGLNGQYRKCSPRDAKCGKIQCQSTQARPLESNAVSIDTTI
  TLNGRRIHCRGTHVYRGPEEEEGEGDMLDPGLVMTGTKCGHNHICFEGQCRNTSFFETEGCGKKCNGHGV
  CNNNKNCHCFPGWSPPFCNTPGDGGSVDSGPLPPKSVGPVIAGVFSALFVLAVLVLLCHCYRQSHKLGKP
  SALPFKLRHQFSCPFRVSQSGGTGHANPTFKLQTPQGKRKVTNTPESLRKPSHPPPRPPPDYLRVESPPA
  PLPAHLNRAAGSSPEAGARIERKESARRPPPSRPMPPAPNCLLSQDFSRPRPPQKALPANPVPGQRTGPR
  SGGTSLLQPPTSGPQPPRPPAVPVPKLPEYRSQRVGAIISSKI
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001291891
• ORF Size: 1809 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001291891.1, NP_001278820.1
• RefSeq Size: 6421
• RefSeq ORF: 1812
• Locus ID: 11492
• MW: 65.2 kDa
• Gene Summary: This gene encodes a cell surface glycoprotein and member of the ADAM (a disintegrin and metalloproteinase) family of endopeptidases. The encoded protein may play a role in the ectodomain shedding of neuregulin proteins. Homozygous knockout mice for this gene exhibit heart development defects and perinatal lethality. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that undergoes proteolytic processing to generate a mature protein product. [provided by RefSeq, Aug 2015]