TRIP (TRAIP) (NM_005879) Human Tagged ORF Clone

CAT#: RC201252L4

Lenti ORF clone of Human TRAF interacting protein (TRAIP), mGFP tagged

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: mGFP
• Symbol: TRAIP
• Synonyms: RNF206; SCKL9; TRIP
• Vector: pLenti-C-mGFP-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC201252).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_005879
• ORF Size: 1407 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_005879.2, NP_005870.2
• RefSeq Size: 2042
• RefSeq ORF: 1410
• Locus ID: 10293
• Domains: RING
• Protein Families: Druggable Genome, Stem cell - Pluripotency
• MW: 53.3 kDa
• Gene Summary: This gene encodes a protein that contains an N-terminal RING finger motif and a putative coiled-coil domain. A similar murine protein interacts with TNFR-associated factor 1 (TRAF1), TNFR-associated factor 2 (TRAF2), and cylindromatosis. The interaction with TRAF2 inhibits TRAF2-mediated nuclear factor kappa-B, subunit 1 activation that is required for cell activation and protection against apoptosis. [provided by RefSeq, Jul 2008]