GNPDA2 (NM_138335) Human Tagged ORF Clone

CAT#: RC202194L4

Lenti ORF clone of Human glucosamine-6-phosphate deaminase 2 (GNPDA2), mGFP tagged

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: mGFP
• Symbol: GNPDA2
• Synonyms: GNP2; SB52
• Vector: pLenti-C-mGFP-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC202194).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_138335
• ORF Size: 420 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_138335.1, NP_612208.1
• RefSeq Size: 2313
• RefSeq ORF: 831
• Locus ID: 132789
• Domains: Glucosamine_iso
• Protein Pathways: Amino sugar and nucleotide sugar metabolism, Metabolic pathways
• MW: 30.9 kDa
• Gene Summary: The protein encoded by this gene is an allosteric enzyme that catalyzes the reversible reaction converting D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium. Variations of this gene have been reported to be associated with influencing body mass index and susceptibility to obesity. A pseudogene of this gene is located on chromosome 9. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012]