AICDA (NM_020661) Human Tagged ORF Clone

CAT#: RC202949L3

Lenti ORF clone of Human activation-induced cytidine deaminase (AICDA), Myc-DDK-tagged

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: AICDA
• Synonyms: AID; ARP2; CDA2; HEL-S-284; HIGM2
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC202949).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_020661
• ORF Size: 594 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_020661.1, NP_065712.1
• RefSeq Size: 2794
• RefSeq ORF: 597
• Locus ID: 57379
• Protein Families: Druggable Genome
• Protein Pathways: Primary immunodeficiency
• MW: 24 kDa
• Gene Summary: This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2). [provided by RefSeq, Feb 2009]