Retinal protein 4 (UNC119) (NM_005148) Human Tagged ORF Clone

CAT#: RC203758L3

Lenti ORF clone of Human unc-119 homolog (C. elegans) (UNC119), transcript variant 1, Myc-DDK-tagged

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: UNC119
• Synonyms: HRG4; IMD13; POC7; POC7A
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC203758).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_005148
• ORF Size: 720 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_005148.2, NP_005139.1
• RefSeq Size: 1398
• RefSeq ORF: 723
• Locus ID: 9094
• Domains: GMP_PDE_delta
• Protein Families: Druggable Genome, Stem cell - Pluripotency
• MW: 27 kDa
• Gene Summary: This gene is specifically expressed in the photoreceptors in the retina. The encoded product shares strong homology with the C. elegans unc119 protein and it can functionally complement the C. elegans unc119 mutation. It has been localized to the photoreceptor synapses in the outer plexiform layer of the retina, and suggested to play a role in the mechanism of photoreceptor neurotransmitter release through the synaptic vesicle cycle. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]