PROCR (NM_006404) Human Tagged ORF Clone

CAT#: RC204858L4

Lenti ORF clone of Human protein C receptor, endothelial (PROCR), mGFP tagged

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: mGFP
• Symbol: PROCR
• Synonyms: CCCA; CCD41; EPCR
• Vector: pLenti-C-mGFP-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC204858).
• Restriction Sites: SgfI-RsrII Cloning Scheme for this gene
• ACCN: NM_006404
• ORF Size: 714 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_006404.3, NP_006395.2
• RefSeq Size: 1506
• RefSeq ORF: 717
• Locus ID: 10544
• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• MW: 26.6 kDa
• Gene Summary: The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer. [provided by RefSeq, Jul 2013]