RASGRP3 (NM_170672) Human Tagged ORF Clone

CAT#: RC206487L2

Lenti ORF clone of Human RAS guanyl releasing protein 3 (calcium and DAG-regulated) (RASGRP3), transcript variant 2, mGFP tagged

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: mGFP
• Symbol: RASGRP3
• Synonyms: GRP3
• Vector: pLenti-C-mGFP
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC206487).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_170672
• ORF Size: 2070 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_170672.1, NP_733772.1
• RefSeq Size: 4711
• RefSeq ORF: 2073
• Locus ID: 25780
• Domains: RasGEFN, RasGEF, EFh, DAG_PE-bind
• Protein Pathways: B cell receptor signaling pathway, MAPK signaling pathway
• MW: 78.3 kDa
• Gene Summary: The protein encoded by this gene is a guanine nucleotide exchange factor that activates the oncogenes HRAS and RAP1A. Defects in this gene have been associated with systemic lupus erythematosus and several cancers. [provided by RefSeq, Mar 2017]