KCNH7 (NM_173162) Human Tagged ORF Clone

CAT#: RC207714

KCNH7 (Myc-DDK-tagged)-Human potassium voltage-gated channel, subfamily H (eag-related), member 7 (KCNH7), transcript variant 2

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: KCNH7
• Synonyms: ERG3; HERG3; Kv11.3
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC207714 representing NM_173162
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCCTGTGCGCAGGGGGCATGTGGCACCACAAAATACATTTCTGGGGACCATCATTCGGAAATTTGAAG
  GGCAAAATAAAAAATTTATCATTGCAAATGCCAGAGTGCAGAACTGTGCCATCATTTATTGCAACGATGG
  GTTCTGTGAGATGACTGGTTTCTCCAGGCCAGATGTCATGCAAAAGCCATGCACCTGCGACTTTCTCCAT
  GGACCCGAGACCAAGAGGCATGATATTGCCCAAATTGCCCAGGCATTGCTGGGGTCAGAAGAGAGGAAAG
  TGGAGGTCACCTACTATCACAAAAATGGGTCCACTTTTATTTGTAACACTCACATAATTCCAGTGAAAAA
  CCAAGAGGGCGTGGCTATGATGTTCATCATTAATTTTGAATATGTGACGGATAATGAAAACGCTGCCACC
  CCAGAGAGGGTAAACCCAATATTACCAATCAAAACTGTAAACCGGAAATTTTTTGGGTTCAAATTCCCTG
  GTCTGAGAGTTCTCACTTACAGAAAGCAGTCCTTACCACAAGAAGACCCCGATGTGGTGGTCATCGATTC
  ATCTAAACACAGTGATGATTCAGTAGCCATGAAGCATTTTAAGTCTCCTACAAAAGAAAGCTGCAGCCCC
  TCTGAAGCAGATGACACAAAAGCTTTGATACAGCCCAGCAAATGTTCTCCCTTGGTGAATATATCCGGAC
  CTCTTGACCATTCCTCTCCCAAAAGGCAATGGGACCGACTCTACCCTGACATGCTGCAGTCAAGTTCCCA
  GCTGTCCCATTCCAGATCAAGGGAAAGCTTATGTAGTATACGGAGAGCATCTTCGGTCCATGATATAGAA
  GGATTCGGCGTCCACCCCAAGAACATATTTAGAGACCGACATGCCAGCGAAGGGCCTTTTAATCATATCA
  AGTCAAGCCTCCTGGGATCCACATCAGATTCAAACCTCAACAAATACAGCACCATTAACAAGATTCCACA
  GCTCACTCTGAATTTTTCAGAGGTCAAAACTGAGAAAAAGAATTCATCACCTCCTTCTTCAGATAAAACC
  ATTATTGCACCCAAGGTTAAAGATCGAACACACAATGTGACTGAGAAAGTGACCCAGGTTCTCTCTTTAG
  GAGCAGATGTCCTACCTGAATACAAACTGCAGACACCACGCATCAACAAGTTTACGATATTGCACTACAG
  CCCTTTCAAGGCAGTCTGGGACTGGCTTATCCTGCTGTTGGTCATATACACTGCTATATTTACTCCCTAC
  TCTGCAGCCTTCCTCCTCAATGACAGAGAAGAACAGAAAAGACGAGAATGTGGCTATTCTTGTAGCCCTT
  TGAATGTGGTAGACTTGATTGTGGATATTATGTTTATCATAGATATTTTAATAAACTTCAGAACAACATA
  TGTAAATCAGAATGAAGAAGTGGTAAGTGATCCCGCCAAAATAGCAATACACTACTTCAAAGGCTGGTTC
  CTGATTGACATGGTTGCAGCAATTCCTTTTGACTTGCTGATTTTTGGATCAGGTTCTGATGAGACAACAA
  CATTAATTGGTCTTTTGAAGACTGCCCGACTCCTCCGTCTTGTGCGCGTGGCCAGGAAACTGGATCGATA
  TTCAGAATATGGCGCTGCTGTTCTAATGCTCTTAATGTGCATCTTTGCCCTGATTGCTCACTGGCTGGCT
  TGCATTTGGTATGCGATTGGGAATGTAGAAAGGCCTTACCTGACTGACAAAATCGGATGGTTGGATTCCT
  TAGGACAGCAAATTGGGAAACGTTACAATGACAGTGACTCAAGTTCTGGACCATCCATTAAAGACAAATA
  CGTCACAGCACTTTATTTTACCTTCAGCAGTTTAACCAGTGTAGGATTCGGGAATGTGTCTCCTAACACG
  AATTCGGAGAAAATCTTTTCAATTTGTGTCATGTTGATTGGCTCACTAATGTATGCAAGCATTTTTGGGA
  ATGTATCTGCAATTATCCAAAGACTATACTCGGGAACTGCCAGGTACCACATGCAGATGCTGCGAGTAAA
  AGAGTTCATTCGCTTTCACCAAATCCCCAACCCTCTGAGGCAACGTCTTGAAGAATATTTCCAGCACGCA
  TGGACTTACACCAATGGCATTGACATGAACATGGTATGTATGTCTGTTTTCCAAAATGAAAGTGCCGCAG
  GCATTATAGTGATAGCCAAAATGGAA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC207714 representing NM_173162
  Red=Cloning site Green=Tags(s)
  
  MPVRRGHVAPQNTFLGTIIRKFEGQNKKFIIANARVQNCAIIYCNDGFCEMTGFSRPDVMQKPCTCDFLH
  GPETKRHDIAQIAQALLGSEERKVEVTYYHKNGSTFICNTHIIPVKNQEGVAMMFIINFEYVTDNENAAT
  PERVNPILPIKTVNRKFFGFKFPGLRVLTYRKQSLPQEDPDVVVIDSSKHSDDSVAMKHFKSPTKESCSP
  SEADDTKALIQPSKCSPLVNISGPLDHSSPKRQWDRLYPDMLQSSSQLSHSRSRESLCSIRRASSVHDIE
  GFGVHPKNIFRDRHASEGPFNHIKSSLLGSTSDSNLNKYSTINKIPQLTLNFSEVKTEKKNSSPPSSDKT
  IIAPKVKDRTHNVTEKVTQVLSLGADVLPEYKLQTPRINKFTILHYSPFKAVWDWLILLLVIYTAIFTPY
  SAAFLLNDREEQKRRECGYSCSPLNVVDLIVDIMFIIDILINFRTTYVNQNEEVVSDPAKIAIHYFKGWF
  LIDMVAAIPFDLLIFGSGSDETTTLIGLLKTARLLRLVRVARKLDRYSEYGAAVLMLLMCIFALIAHWLA
  CIWYAIGNVERPYLTDKIGWLDSLGQQIGKRYNDSDSSSGPSIKDKYVTALYFTFSSLTSVGFGNVSPNT
  NSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHA
  WTYTNGIDMNMVCMSVFQNESAAGIIVIAKME
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_173162
• ORF Size: 2196 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_173162.1, NM_173162.2, NP_775185.1
• RefSeq Size: 2488
• RefSeq ORF: 2199
• Locus ID: 90134
• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Ion Channels: Other, Transmembrane
• MW: 82.7 kDa
• Gene Summary: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. There are at least two alternatively spliced transcript variants derived from this gene and encoding distinct isoforms. [provided by RefSeq, Jul 2008]