PANK4 (NM_018216) Human Tagged ORF Clone

CAT#: RC208116

PANK4 (Myc-DDK-tagged)-Human pantothenate kinase 4 (PANK4)

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: PANK4
• Synonyms: DKFZp547M242; FLJ10782
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC208116 representing NM_018216
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCGGAGTGTGGAGCGAGCGGCAGCGGGAGCAGCGGGGACAGTCTGGACAAGAGCATCACGCTGCCCC
  CCGACGAGATCTTCCGCAACCTGGAGAACGCCAAGCGCTTCGCCATCGACATAGGCGGGTCGTTAACCAA
  GCTGGCCTACTATTCAACGGTACAGCACAAAGTCGCCAAGGTGCGGTCTTTCGACCACTCCGGAAAGGAC
  ACAGAACGTGAACATGAGCCGCCCTATGAGATTTCAGTTCAAGAAGAGATCACTGCTCGACTGCACTTCA
  TTAAGTTTGAGAATACCTACATCGAAGCCTGCCTGGACTTCATCAAAGACCATCTCGTCAACACAGAGAC
  CAAGGTCATCCAGGCGACCGGGGGCGGGGCCTACAAGTTCAAGGACCTCATCGAAGAGAAGCTGCGGCTG
  AAAGTCGACAAGGAGGACGTGATGACGTGCCTGATTAAGGGGTGCAACTTCGTGCTCAAGAACATCCCCC
  ATGAGGCCTTCGTGTACCAGAAGGATTCCGACCCTGAGTTCCGGTTCCAGACCAACCACCCCCACATTTT
  CCCCTATCTTCTTGTCAATATCGGCTCTGGAGTCTCCATCGTGAAGGTGGAGACGGAGGACAGGTTCGAG
  TGGGTCGGCGGCAGCTCCATTGGAGGCGGCACCTTCTGGGGGCTTGGCGCTCTGCTCACCAAAACGAAGA
  AGTTTGACGAGCTCCTGCACCTGGCCTCGAGGGGCCAGCACAGCAATGTGGACATGCTGGTGCGGGACGT
  CTACGGCGGCGCCCACCAGACTCTCGGGCTGAGCGGGAACCTCATCGCCAGCAGCTTCGGGAAGTCGGCC
  ACCGCCGACCAAGAGTTCTCCAAAGAAGACATGGCGAAGAGCCTGCTGCACATGATCAGCAACGACATTG
  GGCAGCTGGCCTGCCTCCACGCACGGCTGCACAGCCTGGACCGCGTGTACTTTGGAGGCTTCTTTATCCG
  GGGCCACCCCGTGACCATGCGCACCATCACCTATAGCATCAACTTCTTCTCCAAGGGGGAAGTGCAGGCG
  CTGTTTCTGAGGCACGAAGGCTACCTGGGAGCCATCGGAGCGTTCCTGAAAGGAGCTGAGCAGGACAATC
  CTAACCAGTACAGCTGGGGAGAGAACTATGCAGGCAGCTCCGGGCTGATGAGTGCATCACCCGAGCTCGG
  CCCGGCGCAGCGGGCGCGGAGTGGCACTTTTGACTTGCTGGAAATGGACCGGCTGGAGAGGCCACTGGTT
  GACCTGCCGCTCCTCCTGGACCCGCCCTCCTACGTGCCCGACACGGTGGACCTCACCGATGACGCTCTGG
  CCCGAAAATACTGGCTCACCTGCTTTGAGGAGGCCCTGGACGGGGTAGTGAAGCGCGCAGTGGCGAGCCA
  GCCAGACTCTGTGGATGCAGCCGAGAGGGCGGAGAAGTTCCGGCAGAAGTACTGGAACAAGCTTCAGACC
  CTGAGGCAGCAGCCCTTCGCCTATGGGACCCTGACCGTGCGCAGCCTGCTGGACACCAGGGAGCACTGTC
  TGAACGAGTTCAACTTCCCGGATCCCTACTCCAAAGTGAAGCAGCGGGAGAATGGCGTGGCGCTGAGGTG
  CTTCCCCGGGGTCGTGCGCTCCCTGGACGCGCTGGGCTGGGAGGAACGGCAGCTGGCGCTGGTGAAAGGC
  CTCCTGGCGGGGAATGTCTTCGACTGGGGGGCCAAAGCCGTGTCTGCTGTCCTTGAATCCGACCCCTACT
  TTGGGTTTGAAGAAGCAAAGAGGAAGTTACAAGAAAGACCCTGGCTCGTGGATTCCTACAGCGAGTGGCT
  TCAGAGATTAAAGGGGCCCCCTCATAAATGTGCCTTAATTTTCGCAGATAACAGTGGAATAGACATCATT
  TTGGGAGTCTTCCCCTTTGTCAGGGAGCTACTCCTTAGAGGGACAGAGGTCATCCTGGCGTGCAACTCAG
  GCCCCGCCCTGAACGACGTGACCCACAGCGAGTCCCTCATCGTGGCAGAGCGTATTGCGGGCATGGACCC
  TGTCGTGCACTCTGCGCTCCAGGAAGAGAGGCTGCTGCTGGTGCAGACGGGCTCCAGCTCCCCGTGCCTC
  GACCTCAGCCGCCTGGATAAGGGGCTGGCCGCACTGGTGCGGGAGCGTGGCGCGGATCTGGTGGTCATCG
  AGGGCATGGGCCGTGCTGTCCACACAAACTACCACGCAGCCCTGCGCTGCGAGAGCCTCAAGCTGGCCGT
  CATCAAGAACGCGTGGCTGGCCGAGCGGCTGGGCGGCCGGCTCTTCAGCGTCATCTTCAAGTACGAGGTC
  CCAGCCGAG
  
  AGCGGACCGACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCC
  TGGATTACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC208116 representing NM_018216
  Red=Cloning site Green=Tags(s)
  
  MAECGASGSGSSGDSLDKSITLPPDEIFRNLENAKRFAIDIGGSLTKLAYYSTVQHKVAKVRSFDHSGKD
  TEREHEPPYEISVQEEITARLHFIKFENTYIEACLDFIKDHLVNTETKVIQATGGGAYKFKDLIEEKLRL
  KVDKEDVMTCLIKGCNFVLKNIPHEAFVYQKDSDPEFRFQTNHPHIFPYLLVNIGSGVSIVKVETEDRFE
  WVGGSSIGGGTFWGLGALLTKTKKFDELLHLASRGQHSNVDMLVRDVYGGAHQTLGLSGNLIASSFGKSA
  TADQEFSKEDMAKSLLHMISNDIGQLACLHARLHSLDRVYFGGFFIRGHPVTMRTITYSINFFSKGEVQA
  LFLRHEGYLGAIGAFLKGAEQDNPNQYSWGENYAGSSGLMSASPELGPAQRARSGTFDLLEMDRLERPLV
  DLPLLLDPPSYVPDTVDLTDDALARKYWLTCFEEALDGVVKRAVASQPDSVDAAERAEKFRQKYWNKLQT
  LRQQPFAYGTLTVRSLLDTREHCLNEFNFPDPYSKVKQRENGVALRCFPGVVRSLDALGWEERQLALVKG
  LLAGNVFDWGAKAVSAVLESDPYFGFEEAKRKLQERPWLVDSYSEWLQRLKGPPHKCALIFADNSGIDII
  LGVFPFVRELLLRGTEVILACNSGPALNDVTHSESLIVAERIAGMDPVVHSALQEERLLLVQTGSSSPCL
  DLSRLDKGLAALVRERGADLVVIEGMGRAVHTNYHAALRCESLKLAVIKNAWLAERLGGRLFSVIFKYEV
  PAE
  
  SGPTRTRRLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-RsrII Cloning Scheme for this gene Plasmid Map
• ACCN: NM_018216
• ORF Size: 2319 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_018216.1, NP_060686.1
• RefSeq Size: 2642
• RefSeq ORF: 2322
• Locus ID: 55229
• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Pantothenate and CoA biosynthesis
• MW: 85.99 kDa
• Gene Summary: This gene encodes a protein belonging to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. This family member is most abundant in muscle but is expressed in all tissues. [provided by RefSeq, Jul 2008]