TIP120A (CAND1) (NM_018448) Human Tagged ORF Clone
CAT#: RC208212L1
- LentiORF®
Lenti ORF clone of Human cullin-associated and neddylation-dissociated 1 (CAND1), Myc-DDK-tagged
"NM_018448" in other vectors (6)
Product Images
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | CAND1 |
Synonyms | TIP120; TIP120A |
Vector | pLenti-C-Myc-DDK |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC208212).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_018448 |
ORF Size | 3690 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_018448.2, NP_060918.2 |
RefSeq Size | 5956 |
RefSeq ORF | 3693 |
Locus ID | 55832 |
Domains | TIP120 |
Protein Families | Transcription Factors |
MW | 136.4 kDa |
Gene Summary | This gene encodes an essential regulator of Cullin-RING ubiquitin ligases, which are in involved in ubiquitinylation of proteins degraded by the Ub proteasome system. The encoded protein binds to unneddylated cullin-RING box protein complexes and acts as an inhibitor of cullin neddylation and of Skp1, cullin, and F box ubiquitin ligase complex assembly and activity. In mammalian cell culture, this protein predominantly localizes to the cytoplasm. Knockdown of this gene in preadipocytes results in blocked adipogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC125317 | CAND1 (untagged)-Human cullin-associated and neddylation-dissociated 1 (CAND1) |
USD 310.00 |
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RC208212 | CAND1 (Myc-DDK-tagged)-Human cullin-associated and neddylation-dissociated 1 (CAND1) |
USD 1,290.00 |
|
RG208212 | CAND1 (GFP-tagged) - Human cullin-associated and neddylation-dissociated 1 (CAND1) |
USD 1,420.00 |
|
RC208212L2 | Lenti ORF clone of Human cullin-associated and neddylation-dissociated 1 (CAND1), mGFP tagged |
USD 1,490.00 |
|
RC208212L3 | Lenti ORF clone of Human cullin-associated and neddylation-dissociated 1 (CAND1), Myc-DDK-tagged |
USD 1,490.00 |
|
RC208212L4 | Lenti ORF clone of Human cullin-associated and neddylation-dissociated 1 (CAND1), mGFP tagged |
USD 1,490.00 |
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