DcR2 (TNFRSF10D) (NM_003840) Human Tagged ORF Clone

CAT#: RC208547L2

Lenti ORF clone of Human tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain (TNFRSF10D), mGFP tagged

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: mGFP
• Symbol: TNFRSF10D
• Synonyms: CD264; DCR2; TRAIL-R4; TRAILR4; TRUNDD
• Vector: pLenti-C-mGFP
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC208547).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_003840
• ORF Size: 1158 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_003840.3, NP_003831.2
• RefSeq Size: 3569
• RefSeq ORF: 1161
• Locus ID: 8793
• Domains: TNFR
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Apoptosis, Cytokine-cytokine receptor interaction, Natural killer cell mediated cytotoxicity
• MW: 41.8 kDa
• Gene Summary: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain, a transmembrane domain, and a truncated cytoplamic death domain. This receptor does not induce apoptosis, and has been shown to play an inhibitory role in TRAIL-induced cell apoptosis. [provided by RefSeq, Jul 2008]