STAT2 (NM_005419) Human Tagged ORF Clone
CAT#: RC208592L4
- LentiORF®
Lenti ORF clone of Human signal transducer and activator of transcription 2, 113kDa (STAT2), transcript variant 1, mGFP tagged
"NM_005419" in other vectors (6)
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | mGFP |
Symbol | STAT2 |
Synonyms | IMD44; ISGF-3; P113; STAT113 |
Vector | pLenti-C-mGFP-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC208592).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_005419 |
ORF Size | 2553 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers. |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_005419.2, NP_005410.1 |
RefSeq Size | 4576 bp |
RefSeq ORF | 2556 bp |
Locus ID | 6773 |
UniProt ID | P52630, R9QE65 |
Cytogenetics | 12q13.3 |
Domains | SH2, STAT |
Protein Families | Druggable Genome, Transcription Factors |
Protein Pathways | Chemokine signaling pathway, Jak-STAT signaling pathway |
MW | 97.9 kDa |
Gene Summary | 'The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. The protein mediates innate antiviral activity. Mutations in this gene result in Immunodeficiency 44. [provided by RefSeq, Aug 2020]' |
Documents
Product Manuals |
FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC108848 | STAT2 (untagged)-Human signal transducer and activator of transcription 2, 113kDa (STAT2), transcript variant 1 |
USD 310.00 |
|
RC208592 | STAT2 (Myc-DDK-tagged)-Human signal transducer and activator of transcription 2, 113kDa (STAT2), transcript variant 1 |
USD 750.00 |
|
RG208592 | STAT2 (GFP-tagged) - Human signal transducer and activator of transcription 2, 113kDa (STAT2), transcript variant 1 |
USD 830.00 |
|
RC208592L1 | Lenti ORF clone of Human signal transducer and activator of transcription 2, 113kDa (STAT2), transcript variant 1, Myc-DDK-tagged |
USD 1,176.00 |
|
RC208592L2 | Lenti ORF clone of Human signal transducer and activator of transcription 2, 113kDa (STAT2), transcript variant 1, mGFP tagged |
USD 1,176.00 |
|
RC208592L3 | Lenti ORF clone of Human signal transducer and activator of transcription 2, 113kDa (STAT2), transcript variant 1, Myc-DDK-tagged |
USD 950.00 |
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