PP4R1 (PPP4R1) (NM_005134) Human Tagged ORF Clone

CAT#: RC209255L4

Lenti ORF clone of Human protein phosphatase 4, regulatory subunit 1 (PPP4R1), transcript variant 2, mGFP tagged

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: mGFP
• Symbol: PPP4R1
• Synonyms: MEG1; PP4(Rmeg); PP4R1
• Vector: pLenti-C-mGFP-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC209255).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_005134
• ORF Size: 2799 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_005134.1, NP_005125.1
• RefSeq Size: 3929
• RefSeq ORF: 2802
• Locus ID: 9989
• Domains: HEAT
• Protein Families: Druggable Genome, Phosphatase
• MW: 105.2 kDa
• Gene Summary: This gene encodes one of several alternate regulatory subunits of serine/threonine protein phosphatase 4 (PP4). The protein features multiple HEAT repeats. This protein forms a complex with PP4RC. This complex may have a distinct role from other PP4 complexes, including regulation of HDAC3 (Zhang et al., PMID: 15805470). There is also a transcribed pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]