BMPER (NM_133468) Human Tagged ORF Clone

CAT#: RC209319

BMPER (Myc-DDK-tagged)-Human BMP binding endothelial regulator (BMPER)

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: BMPER
• Synonyms: CRIM3; CV-2; CV2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC209319 ORF sequence
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCTCTGGTTCTCCGGCGTCGGGGCTCTGGCTGAGCGTTACTGCCGCCGCTCGCCTGGGATTACGTGCT
  GCGTCTTGCTGCTACTCAATTGCTCGGGGGTCCCCATGTCTCTGGCTTCCTCCTTCTTGACAGGTTCTGT
  TGCAAAATGTGAAAATGAAGGTGAAGTCCTCCAGATTCCATTTATCACAGACAACCCTTGCATAATGTGT
  GTCTGCTTGAACAAGGAAGTGACACGTAAGAGAGAGAAGTGCCCCGTGCTGTCCCGAGACTGTGCCCTGG
  CCATCAAGCAGAGGGGAGCCTGTTGTGAACAGTGCAAAGGTTGCACCTATGAAGGAAATACCTATAACAG
  CTCCTTCAAATGGCAGAGCCCGGCTGAGCCTTGTGTTCTACGCCAGTGCCAGGAGGGTGTTGTCACAGAG
  TCTGGGGTGCGCTGTGTTGTTCATTGTAAAAACCCTTTGGAGCATCTGGGAATGTGCTGCCCCACATGTC
  CAGGCTGTGTGTTTGAGGGTGTGCAGTATCAAGAAGGGGAGGAATTTCAGCCAGAAGGAAGCAAATGTAC
  CAAGTGTTCCTGCACTGGAGGCAGGACACAATGTGTGAGAGAAGTCTGTCCCATTCTCTCCTGTCCCCAG
  CACCTTAGTCACATACCCCCAGGACAGTGCTGCCCCAAATGTTTGGGTCAGAGGAAAGTGTTTGACCTCC
  CTTTTGGGAGCTGCCTCTTTCGAAGTGATGTTTATGACAATGGATCCTCATTTCTGTACGATAACTGCAC
  AGCTTGTACCTGCAGGGACTCTACTGTGGTTTGCAAGAGGAAGTGCTCCCACCCTGGTGGCTGTGACCAA
  GGCCAGGAGGGCTGTTGTGAAGAGTGCCTCCTACGAGTGCCCCCAGAAGACATCAAAGTATGCAAATTTG
  GCAACAAGATTTTCCAGGATGGAGAGATGTGGTCCTCTATCAATTGTACCATCTGTGCTTGTGTGAAAGG
  CAGGACGGAGTGTCGCAATAAGCAGTGCATTCCCATCAGTAGCTGCCCACAGGGCAAAATTCTCAACAGA
  AAAGGATGCTGTCCTATTTGCACTGAAAAGCCCGGCGTTTGCACGGTGTTTGGAGATCCCCACTACAACA
  CTTTTGACGGTCGGACATTTAACTTTCAGGGGACGTGTCAGTACGTTTTGACAAAAGACTGCTCCTCCCC
  TGCCTCGCCCTTCCAGGTGCTGGTGAAGAACGACGCCCGCCGGACACGCTCCTTCTCGTGGACCAAGTCG
  GTGGAGCTGGTGCTGGGCGAGAGCAGGGTCAGCCTGCAGCAGCACCTCACCGTGCGCTGGAACGGCTCGC
  GCATCGCGCTCCCCTGCCGCGCGCCACACTTCCACATCGACCTGGATGGCTACCTCTTGAAAGTGACCAC
  CAAAGCAGGTTTGGAAATATCTTGGGATGGAGACAGTTTTGTAGAAGTCATGGCTGCGCCGCATCTCAAG
  GGCAAGCTCTGTGGTCTTTGTGGCAACTACAATGGACATAAACGTGATGACTTAATTGGTGGAGATGGAA
  ACTTCAAGTTTGATGTGGATGACTTTGCTGAATCTTGGAGGGTGGAGTCCAATGAGTTCTGCAACAGACC
  TCAGAGAAAGCCAGTGCCTGAACTGTGTCAAGGGACAGTCAAGGTAAAGCTCCGGGCCCATCGAGAATGC
  CAAAAGCTCAAATCCTGGGAGTTTCAGACCTGCCACTCGACTGTGGACTACGCCACTTTCTACCGGTCCT
  GTGTGACAGACATGTGTGAATGTCCAGTCCATAAAAACTGTTATTGCGAGTCATTTTTGGCATATACCCG
  GGCCTGCCAGAGAGAGGGCATCAAAGTCCACTGGGAGCCTCAGCAGAATTGTGCAGCCACCCAGTGTAAG
  CATGGTGCTGTGTACGATACCTGTGGTCCGGGATGTATCAAGACCTGTGACAACTGGAATGAAATTGGTC
  CATGCAACAAGCCGTGCGTTGCTGGGTGCCACTGTCCAGCAAACTTGGTCCTTCACAAGGGAAGGTGCAT
  CAAGCCAGTCCTTTGTCCCCAGCGG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC209319 protein sequence
  Red=Cloning site Green=Tags(s)
  
  MLWFSGVGALAERYCRRSPGITCCVLLLLNCSGVPMSLASSFLTGSVAKCENEGEVLQIPFITDNPCIMC
  VCLNKEVTRKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVTE
  SGVRCVVHCKNPLEHLGMCCPTCPGCVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQ
  HLSHIPPGQCCPKCLGQRKVFDLPFGSCLFRSDVYDNGSSFLYDNCTACTCRDSTVVCKRKCSHPGGCDQ
  GQEGCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILNR
  KGCCPICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDARRTRSFSWTKS
  VELVLGESRVSLQQHLTVRWNGSRIALPCRAPHFHIDLDGYLLKVTTKAGLEISWDGDSFVEVMAAPHLK
  GKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRPQRKPVPELCQGTVKVKLRAHREC
  QKLKSWEFQTCHSTVDYATFYRSCVTDMCECPVHKNCYCESFLAYTRACQREGIKVHWEPQQNCAATQCK
  HGAVYDTCGPGCIKTCDNWNEIGPCNKPCVAGCHCPANLVLHKGRCIKPVLCPQR
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_133468
• ORF Size: 2055 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_133468.1, NM_133468.2, NM_133468.3, NM_133468.4, NP_597725.1
• RefSeq Size: 5031
• RefSeq ORF: 2058
• Locus ID: 168667
• Protein Families: Secreted Protein
• MW: 76 kDa
• Gene Summary: This gene encodes a secreted protein that interacts with, and inhibits bone morphogenetic protein (BMP) function. It has been shown to inhibit BMP2- and BMP4-dependent osteoblast differentiation and BMP-dependent differentiation of the chondrogenic cells. Mutations in this gene are associated with a lethal skeletal disorder, diaphanospondylodysostosis. [provided by RefSeq, Dec 2011]