NSD3 (NM_023034) Human Tagged ORF Clone

CAT#: RC210993L3

Lenti ORF clone of Human Wolf-Hirschhorn syndrome candidate 1-like 1 (WHSC1L1), transcript variant long, Myc-DDK-tagged

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: NSD3
• Synonyms: KMT3F; KMT3G; pp14328; WHISTLE; WHSC1L1
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC210993).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_023034
• ORF Size: 4311 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_023034.1, NP_075447.1
• RefSeq Size: 5431
• RefSeq ORF: 4314
• Locus ID: 54904
• Domains: PWWP, SET, PHD, PostSET, AWS
• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Lysine degradation
• MW: 161.6 kDa
• Gene Summary: This gene is related to the Wolf-Hirschhorn syndrome candidate-1 gene and encodes a protein with PWWP (proline-tryptophan-tryptophan-proline) domains. This protein methylates histone H3 at lysine residues 4 and 27, which represses gene transcription. Two alternatively spliced variants have been described. [provided by RefSeq, May 2015]