GLP1R (NM_002062) Human Tagged ORF Clone
CAT#: RC211333L4
- LentiORF®
Lenti ORF clone of Human glucagon-like peptide 1 receptor (GLP1R), mGFP tagged
"NM_002062" in other vectors (6)
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | mGFP |
Symbol | GLP1R |
Synonyms | GLP-1; GLP-1-R; GLP-1R |
Vector | pLenti-C-mGFP-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC211333).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_002062 |
ORF Size | 1389 bp |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers. |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_002062.2, NP_002053.2 |
RefSeq Size | 3071 bp |
RefSeq ORF | 1392 bp |
Locus ID | 2740 |
UniProt ID | P43220, A0A142FHB8 |
Cytogenetics | 6p21.2 |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, GPCR, Transmembrane |
Protein Pathways | Neuroactive ligand-receptor interaction |
MW | 52.8 kDa |
Gene Summary | 'This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016]' |
Documents
Product Manuals |
FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC124060 | GLP1R (untagged)-Human glucagon-like peptide 1 receptor (GLP1R) |
USD 760.00 |
|
RC211333 | GLP1R (Myc-DDK-tagged)-Human glucagon-like peptide 1 receptor (GLP1R) |
USD 420.00 |
|
RG211333 | GLP1R (GFP-tagged) - Human glucagon-like peptide 1 receptor (GLP1R) |
USD 460.00 |
|
RC211333L1 | Lenti ORF clone of Human glucagon-like peptide 1 receptor (GLP1R), Myc-DDK-tagged |
USD 768.00 |
|
RC211333L2 | Lenti ORF clone of Human glucagon-like peptide 1 receptor (GLP1R), mGFP tagged |
USD 768.00 |
|
RC211333L3 | Lenti ORF clone of Human glucagon-like peptide 1 receptor (GLP1R), Myc-DDK-tagged |
USD 620.00 |
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