WNK2 (NM_006648) Human Tagged ORF Clone

CAT#: RC212364

WNK2 (Myc-DDK-tagged)-Human WNK lysine deficient protein kinase 2 (WNK2)

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: WNK2
• Synonyms: NY-CO-43; P/OKcl.13; PRKWNK2; SDCCAG43
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC212364 representing NM_006648
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGACGGCGATGGCGGCCGCCGAGACGTCCCCGGCACGCTGATGGAGCCCGGGCGCGGCGCGGGGCCCG
  CGGGCATGGCGGAGCCTCGGGCGAAGGCGGCGCGGCCGGGGCCCCAGCGCTTTCTGCGGCGCAGCGTGGT
  AGAGTCGGACCAGGAGGAGCCGCCGGGCTTGGAGGCAGCCGAGGCGCCGGGCCCGCAGCCCCCGCAGCCC
  CTGCAGCGCCGGGTGCTTCTGCTCTGCAAGACGCGCCGCCTCATCGCGGAGCGCGCCCGCGGACGCCCCG
  CCGCCCCCGCGCCCGCAGCGCTGGTAGCGCAGCCGGGAGCCCCCGGAGCCCCCGCGGACGCCGGCCCCGA
  GCCCGTGGGCACGCAGGAGCCCGGCCCGGACCCCATCGCAGCCGCTGTCGAAACCGCGCCTGCCCCCGAC
  GGCGGCCCCAGGGAGGAGGCGGCGGCGACCGTGAGGAAGGAGGATGAGGGGGCGGCCGAGGCGAAGCCTG
  AGCCCGGGCGCACTCGCCGGGACGAGCCCGAAGAGGAGGAGGACGACGAGGACGACCTCAAGGCCGTGGC
  CACCTCTCTGGACGGCCGCTTCCTCAAGTTCGACATCGAGCTGGGCCGCGGTTCCTTCAAGACGGTCTAC
  AAGGGGCTGGACACGGAGACCTGGGTGGAGGTGGCCTGGTGTGAGCTGCAGGACCGGAAGCTCACCAAGC
  TGGAGCGGCAGCGGTTCAAGGAAGAGGCTGAGATGCTGAAAGGCCTGCAGCACCCCAACATCGTGCGCTT
  CTACGACTTCTGGGAGTCCAGCGCCAAGGGCAAGCGGTGCATTGTGCTGGTGACGGAGCTGATGACCTCA
  GGGACGCTGAAGACATACCTGAAGCGGTTCAAGGTGATGAAGCCCAAGGTTCTCCGCAGCTGGTGCCGGC
  AGATCCTGAAGGGCCTGCTGTTCCTGCACACAAGGACGCCACCCATCATCCACCGAGACCTGAAATGTGA
  CAATATTTTCATCACCGGACCAACTGGGTCTGTGAAGATTGGCGACTTGGGCCTGGCCACTCTGAAAAGA
  GCGTCATTTGCCAAAAGTGTGATAGGTACTCCCGAGTTCATGGCGCCCGAGATGTACGAGGAGCACTACG
  ATGAGTCCGTGGACGTCTATGCCTTTGGGATGTGCATGCTGGAGATGGCCACCTCGGAGTACCCCTACTC
  GGAGTGCCAGAATGCGGCCCAGATCTACCGCAAGGTCACCTGTGGTATCAAGCCGGCCAGCTTTGAGAAA
  GTGCACGATCCTGAAATCAAGGAGATTATTGGGGAGTGTATCTGCAAAAACAAGGAGGAAAGGTACGAGA
  TCAAAGACCTGCTGAGCCACGCCTTCTTCGCAGAGGACACAGGCGTGAGGGTGGAGCTCGCGGAGGAGGA
  CCACGGCAGGAAGTCCACCATCGCCCTGAGGCTCTGGGTGGAAGACCCCAAGAAACTGAAGGGAAAGCCC
  AAGGACAATGGAGCCATAGAGTTCACCTTCGACCTGGAGAAGGAGACGCCGGATGAGGTGGCCCAAGAGA
  TGATTGAGTCTGGATTCTTCCACGAGAGTGACGTCAAGATCGTGGCCAAGTCCATCCGTGACCGCGTGGC
  CTTGATCCAGTGGCGGCGGGAGAGGATCTGGCCCGCGCTGCAGCCCAAGGAGCAGCAGGATGTGGGCAGC
  CCGGACAAGGCCAGGGGTCCGCCGGTGCCCCTGCAGGTCCAGGTGACCTACCATGCACAGGCTGGGCAGC
  CCGGGCCACCAGAGCCCGAGGAGCCGGAGGCCGACCAGCACCTCCTGCCACCTACGTTGCCGACCAGCGC
  CACCTCCCTGGCCTCGGACAGCACCTTCGACAGCGGCCAGGGCTCTACCGTGTACTCAGACTCGCAGAGC
  AGCCAGCAGAGCGTGATGCTTGGCTCCCTTGCCGACGCAGCGCCGTCCCCGGCCCAGTGTGTGTGCAGCC
  CCCCTGTGAGCGAGGGGCCCGTCCTGCCGCAGAGCCTGCCCTCGCTGGGGGCCTACCAGCAGCCCACGGC
  TGCACCTGGCTTGCCGGTGGGCTCTGTCCCGGCCCCCGCCTGCCCTCCGTCCCTCCAGCAGCACTTCCCG
  GATCCGGCCATGAGCTTCGCCCCCGTGCTGCCGCCGCCCAGCACCCCCATGCCCACGGGCCCAGGCCAGC
  CAGCACCCCCCGGCCAGCAGCCTCCTCCGCTGGCCCAGCCGACACCCCTGCCGCAGGTCCTGGCCCCACA
  GCCCGTGGTCCCCCTCCAGCCGGTTCCCCCCCACCTGCCACCGTACCTGGCTCCAGCCTCCCAGGTGGGG
  GCCCCCGCTCAGCTGAAGCCCCTCCAGATGCCACAGGCGCCCCTGCAGCCGCTTGCTCAAGTCCCTCCGC
  AGATGCCCCCGATTCCTGTTGTGCCCCCCATCACGCCCCTGGCGGGAATCGACGGCCTCCCTCCGGCCCT
  CCCAGACCTGCCGACCGCGACTGTGCCTCCCGTGCCACCACCTCAGTATTTCTCTCCAGCCGTGATCTTG
  CCGAGCCTCGCTGCCCCACTCCCCCCTGCGTCCCCAGCCTTGCCTCTGCAGGCTGTGAAGCTGCCCCACC
  CCCCTGGGGCGCCCCTGGCCATGCCCTGCCGGACCATTGTGCCAAATGCACCGGCCACTATCCCCCTGCT
  GGCCGTAGCCCCACCGGGCGTGGCTGCCCTGTCCATTCATTCTGCCGTGGCCCAGCTCCCAGGCCAACCT
  GTGTACCCAGCGGCCTTCCCACAGATGGCGCCTACTGACGTCCCTCCTTCCCCCCATCACACGGTGCAGA
  ATATGAGGGCCACCCCTCCACAGCCGGCACTGCCTCCACAACCCACACTGCCCCCACAACCCGTGCTGCC
  CCCGCAACCCACGCTGCCCCCTCAACCTGTGTTGCCCCCGCAACCCACACGGCCCCCTCAACCTGTGCTG
  CCCCCGCAACCCATGCTGCCCCCACAACCTGTGCTGCCCCCGCAGCCGGCACTGCCTGTGCGCCCTGAGC
  CCCTCCAGCCCCACCTTCCTGAACAAGCTGCTCCAGCTGCTACACCAGGGAGCCAGATTCTGCTTGGCCA
  CCCAGCTCCCTATGCTGTGGACGTCGCCGCTCAGGTCCCCACCGTGCCTGTGCCACCGGCTGCGGTCCTC
  TCGCCGCCTCTGCCGGAAGTGCTGCTGCCTGCCGCCCCTGAGCTCCTGCCTCAGTTCCCCAGCTCCCTGG
  CCACGGTGTCTGCCTCTGTGCAGAGTGTGCCCACCCAGACTGCCACACTTCTGCCACCAGCAAACCCACC
  GCTGCCTGGCGGGCCCGGGATCGCCAGCCCTTGCCCAACTGTCCAGCTGACGGTGGAACCAGTCCAAGAG
  GAGCAGGCCTCACAGGACAAGCCGCCCGGCCTCCCGCAGAGCTGTGAGAGCTATGGAGGTTCTGATGTCA
  CTTCTGGAAAAGAGCTGAGTGACAGCTGTGAAGGCGCCTTTGGAGGGGGCAGGCTGGAGGGCAGGGCAGC
  CCGAAAACACCACCGCAGGTCCACGCGTGCGCGCTCCCGGCAGGAGAGGGCCAGCCGGCCCCGGCTTACC
  ATCTTGAACGTGTGCAACACTGGGGACAAGATGGTGGAGTGCCAGCTGGAGACGCACAACCACAAGATGG
  TGACCTTCAAGTTCGACTTGGACGGGGACGCACCCGATGAAATTGCCACGTATATGGTGGAGCATGACTT
  TATCCTGCAGGCCGAGCGGGAAACGTTCATCGAGCAGATGAAGGATGTCATGGACAAGGCAGAGGACATG
  CTCAGCGAGGACACAGACGCCGACCGTGGCTCCGACCCAGGGACCAGCCCGCCACACCTCAGCACCTGCG
  GCCTGGGCACCGGGGAGGAGAGCCGACAATCCCAAGCCAACGCCCCCGTGTATCAGCAGAACGTCCTGCA
  CACCGGGAAGAGGTGGTTCATCATCTGTCCGGTGGCTGAGCACCCCGCCCCCGAGGCCCCTGAATCTTCG
  CCCCCACTTCCTCTAAGCTCCCTGCCGCCAGAAGCCAGCCAAGATTCAGCGCCCTATAAAGACCAGCTGT
  CCTCGAAGGAACAACCCAGCTTTCTAGCCAGTCAGCAGCTCCTGAGCCAGGCGGGCCCCAGCAACCCTCC
  TGGGGCACCCCCAGCCCCTTTGGCCCCCTCCTCCCCTCCTGTGACTGCTCTGCCCCAAGATGGAGCAGCT
  CCAGCCACCAGCACCATGCCAGAGCCAGCGTCAGGAACTGCCAGCCAGGCAGGGGGTCCAGGGACACCTC
  AGGGGCTGACCAGTGAGCTCGAGACGTCTCAGCCACTAGCGGAGACTCACGAGGCCCCGCTTGCTGTGCA
  GCCCCTCGTGGTGGGCCTAGCACCTTGCACTCCAGCTCCAGAGGCTGCCTCAACCAGGGACGCCAGTGCC
  CCAAGGGAGCCCCTGCCACCTCCTGCACCTGAGCCCAGCCCCCACAGCGGGACCCCACAGCCCGCCTTGG
  GTCAACCTGCTCCCCTGCTTCCTGCCGCAGTGGGGGCCGTCAGCCTGGCCACCTCCCAGCTCCCAAGCCC
  ACCCCTGGGGCCCACCGTCCCCCCACAGCCACCCTCGGCCCTGGAGTCGGATGGGGAAGGGCCGCCCCCC
  AGGGTGGGCTTTGTGGACAGCACCATCAAGAGCCTGGACGAGAAGCTGCGGACTCTGCTCTACCAGGAGC
  ACGTGCCCACCTCCTCAGCCTCAGCTGGGACCCCTGTGGAGGTGGGCGACAGAGACTTCACCCTGGAGCC
  CCTGAGAGGGGACCAGCCCCGCTCAGAGGTCTGCGGGGGGGACCTGGCCCTGCCCCCAGTGCCTAAGGAG
  GCGGTCTCAGGGCGTGTCCAGCTGCCCCAGCCCTTGGTGGAGAAGTCAGAACTGGCCCCCACTCGAGGGG
  CCGTGATGGAGCAGGGCACGTCCTCGTCAATGACAGCAGAGTCGTCTCCCAGGAGTATGCTAGGCTATGA
  CAGAGATGGAAGGCAGGTGGCCTCAGACTCCCATGTGGTCCCCAGCGTCCCCCAGGATGTACCTGCTTTT
  GTGAGACCTGCACGTGTGGAGCCCACAGACAGGGATGGTGGAGAAGCTGGAGAAAGCTCGGCAGAGCCCC
  CGCCGAGTGACATGGGCACAGTGGGGGGCCAGGCTAGCCACCCCCAGACACTCGGCGCTCGAGCTTTGGG
  GTCCCCTCGGAAACGTCCAGAGCAGCAGGATGTCAGCTCACCAGCCAAGACTGTGGGCCGTTTCTCGGTG
  GTCAGCACTCAGGACGAGTGGACCCTGGCCTCCCCCCACAGCCTGAGATACTCTGCCCCACCCGACGTCT
  ACCTGGACGAGGCCCCCTCCAGCCCCGACGTGAAGCTGGCAGTGCGGCGGGCGCAGACGGCCTCCTCCAT
  CGAGGTCGGCGTGGGCGAGCCCGTGTCCAGCGACTCTGGGGACGAGGGCCCTCGGGCGAGACCCCCGGTG
  CAGAAGCAGGCGTCCCTGCCCGTGAGTGGCAGCGTGGCTGGCGACTTCGTGAAGAAGGCCACCGCCTTCC
  TGCAGAGGCCTTCTCGGGCCGGCTCGCTGGGCCCCGAGACACCCAGCAGGGTGGGCATGAAGGTCCCCAC
  GATCAGCGTGACCTCCTTCCATTCCCAGTCGTCCTACATCAGCAGCGACAATGATTCGGAGCTCGAGGAT
  GCTGACATAAAGAAGGAGCTGCAGAGTCTGCGGGAGAAGCACCTGAAGGAGATCTCGGAGCTGCAGAGCC
  AGCAGAAGCAGGAGATCGAAGCTCTGTACCGCCGCCTGGGCAAGCCACTGCCCCCCAACGTGGGCTTCTT
  CCACACGGCACCCCCCACTGGCCGCCGGAGAAAAACCAGCAAGAGCAAGCTGAAGGCAGGCAAGCTGCTA
  AATCCCCTGGTGCGGCAGCTCAAGGTCGTGGCCTCCAGCACAGGTCACTTGGCTGACTCCAGCAGAGGCC
  CTCCCGCTAAGGACCCTGCCCAAGCCAGTGTGGGGCTCACTGCAGACAGCACGGGCCTGAGCGGGAAGGC
  AGTGCAGACCCAGCAGCCCTGCTCCGTCCGGGCCTCCCTGTCTTCGGACATCTGCTCCGGCTTAGCCAGT
  GATGGAGGCGGAGCGCGTGGCCAAGGCTGGACGGTTTACCACCCAACGTCTGAGAGAGTGACCTATAAGT
  CTAGTAGCAAACCTCGTGCTCGATTCCTCAGTGGACCCGTATCTGTGTCCATCTGGTCTGCCCTGAAGCG
  TCTCTGCCTAGGCAAAGAACACAGCAGTAGGTCCTCCACCAGCAGCCTGGCCCCAGGCCCTGAGCCAGGC
  CCCCAGCCCGCCCTGCACGTCCAGGCGCAGGTGAACAACAGCAACAACAAGAAGGGTACCTTCACGGACG
  ACCTGCACAAGCTGGTGGACGAGTGGACGAGCAAGACGGTGGGGGCCGCGCAGCTGAAGCCCACGCTCAA
  CCAGCTGAAGCAGACCCAGAAGCTGCAAGACATGGAGGCCCAGGCAGGCTGGGCTGCCCCTGGCGAGGCG
  CGGGCTATGACCGCACCTCGAGCAGGAGTGGGGATGCCACGTCTGCCCCCAGCGCCCGGCCCTCTGTCCA
  CCACGGTCATTCCCGGAGCCGCCCCGACCCTGTCCGTGCCCACACCAGATCCTGAGAGTGAGAAGCCTGA
  C
  
  AGCGGACCGACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCC
  TGGATTACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC212364 representing NM_006648
  Red=Cloning site Green=Tags(s)
  
  MDGDGGRRDVPGTLMEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGPQPPQP
  LQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVGTQEPGPDPIAAAVETAPAPD
  GGPREEAAATVRKEDEGAAEAKPEPGRTRRDEPEEEEDDEDDLKAVATSLDGRFLKFDIELGRGSFKTVY
  KGLDTETWVEVAWCELQDRKLTKLERQRFKEEAEMLKGLQHPNIVRFYDFWESSAKGKRCIVLVTELMTS
  GTLKTYLKRFKVMKPKVLRSWCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKR
  ASFAKSVIGTPEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEK
  VHDPEIKEIIGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHGRKSTIALRLWVEDPKKLKGKP
  KDNGAIEFTFDLEKETPDEVAQEMIESGFFHESDVKIVAKSIRDRVALIQWRRERIWPALQPKEQQDVGS
  PDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLPPTLPTSATSLASDSTFDSGQGSTVYSDSQS
  SQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFP
  DPAMSFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVG
  APAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVIL
  PSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQP
  VYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVL
  PPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVPPAAVL
  SPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQE
  EQASQDKPPGLPQSCESYGGSDVTSGKELSDSCEGAFGGGRLEGRAARKHHRRSTRARSRQERASRPRLT
  ILNVCNTGDKMVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDM
  LSEDTDADRGSDPGTSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAPEAPESS
  PPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAPLAPSSPPVTALPQDGAA
  PATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASA
  PREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPP
  RVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLALPPVPKE
  AVSGRVQLPQPLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAF
  VRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVSSPAKTVGRFSV
  VSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVGVGEPVSSDSGDEGPRARPPV
  QKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGPETPSRVGMKVPTISVTSFHSQSSYISSDNDSELED
  ADIKKELQSLREKHLKEISELQSQQKQEIEALYRRLGKPLPPNVGFFHTAPPTGRRRKTSKSKLKAGKLL
  NPLVRQLKVVASSTGHLADSSRGPPAKDPAQASVGLTADSTGLSGKAVQTQQPCSVRASLSSDICSGLAS
  DGGGARGQGWTVYHPTSERVTYKSSSKPRARFLSGPVSVSIWSALKRLCLGKEHSSRSSTSSLAPGPEPG
  PQPALHVQAQVNNSNNKKGTFTDDLHKLVDEWTSKTVGAAQLKPTLNQLKQTQKLQDMEAQAGWAAPGEA
  RAMTAPRAGVGMPRLPPAPGPLSTTVIPGAAPTLSVPTPDPESEKPD
  
  SGPTRTRRLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-RsrII Cloning Scheme for this gene Plasmid Map
• ACCN: NM_006648
• ORF Size: 6651 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_006648.3, NP_006639.3
• RefSeq Size: 6834
• RefSeq ORF: 6654
• Locus ID: 65268
• Protein Families: Druggable Genome, Protein Kinase
• MW: 234.2 kDa
• Gene Summary: The protein encoded by this gene is a cytoplasmic serine-threonine kinase that belongs to the protein kinase superfamily. The protein plays an important role in the regulation of electrolyte homeostasis, cell signaling survival, and proliferation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]