IRX5 (NM_005853) Human Tagged ORF Clone

CAT#: RC212385L4

Lenti-ORF clone of IRX5 (mGFP-tagged)-Human iroquois homeobox 5 (IRX5)

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: mGFP
• Symbol: IRX5
• Synonyms: HMMS; IRX-2a; IRXB2
• Vector: pLenti-C-mGFP-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC212385).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_005853
• ORF Size: 1449 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_005853.5, NP_005844.3, NP_005844.4
• RefSeq Size: 2078
• RefSeq ORF: 1452
• Locus ID: 10265
• Protein Families: Transcription Factors
• MW: 50.8 kDa
• Gene Summary: This gene encodes a member of the iroquois homeobox gene family, which are involved in several embryonic developmental processes. Knockout mice lacking this gene show that it is required for retinal cone bipolar cell differentiation, and that it negatively regulates potassium channel gene expression in the heart to ensure coordinated cardiac repolarization. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]