CABP (CABP1) (NM_004276) Human Tagged ORF Clone

CAT#: RC212438

CABP1 (Myc-DDK-tagged)-Human calcium binding protein 1 (CABP1), transcript variant 2

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: CABP1
• Synonyms: CALBRAIN; HCALB_BR
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC212438 representing NM_004276
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGGCAACTGTGTCAAGTATCCACTGAGAAATCTCTCAAGGAAGGATAGATCACTGCGACCAGAGGAAA
  TTGAAGAGCTCCGAGAGGCCTTCAGAGAATTCGACAAGGACAAGGATGGCTACATCAACTGCCGGGATCT
  GGGCAACTGCATGCGCACCATGGGCTACATGCCCACCGAGATGGAGCTCATCGAACTGTCCCAGCAGATC
  AACATGAACCTGGGTGGCCATGTAGATTTTGATGACTTCGTGGAGCTAATGGGGCCTAAACTCCTGGCAG
  AGACAGCAGATATGATTGGTGTAAAGGAACTGCGAGATGCTTTCCGAGAGTTTGACACCAATGGTGATGG
  GGAAATAAGCACCAGTGAGCTGCGAGAGGCTATGAGGAAGCTCCTGGGTCATCAGGTGGGACACCGAGAC
  ATAGAGGAAATTATCCGAGATGTGGACCTCAATGGGGATGGACGAGTGGACTTTGAAGAGTTTGTCCGGA
  TGATGTCCCGC
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC212438 representing NM_004276
  Red=Cloning site Green=Tags(s)
  
  MGNCVKYPLRNLSRKDRSLRPEEIEELREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEMELIELSQQI
  NMNLGGHVDFDDFVELMGPKLLAETADMIGVKELRDAFREFDTNGDGEISTSELREAMRKLLGHQVGHRD
  IEEIIRDVDLNGDGRVDFEEFVRMMSR
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_004276
• ORF Size: 501 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_004276.2, NM_004276.3, NM_004276.4, NP_004267.2
• RefSeq Size: 1082
• RefSeq ORF: 504
• Locus ID: 9478
• Domains: EFh
• MW: 19.4 kDa
• Gene Summary: Calcium binding proteins are an important component of calcium mediated cellular signal transduction. This gene encodes a protein that belongs to a subfamily of calcium binding proteins which share similarity to calmodulin. The protein encoded by this gene regulates the gating of voltage-gated calcium ion channels. This protein inhibits calcium-dependent inactivation and supports calcium-dependent facilitation of ion channels containing voltage-dependent L-type calcium channel subunit alpha-1C. This protein also regulates calcium-dependent activity of inositol 1,4,5-triphosphate receptors, P/Q-type voltage-gated calcium channels, and transient receptor potential channel TRPC5. This gene is predominantly expressed in retina and brain. Alternative splicing results in multiple transcript variants encoding disinct isoforms. [provided by RefSeq, Jul 2012]