Plexin B2 (PLXNB2) (NM_012401) Human Tagged ORF Clone

CAT#: RC213651

PLXNB2 (Myc-DDK-tagged)-Human plexin B2 (PLXNB2)

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: PLXNB2
• Synonyms: dJ402G11.3; MM1; Nbla00445; PLEXB2
• Vector: pCMV6-AC-Myc-DDK
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC213651 representing NM_012401
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCACTGCAGCTCTGGGCCCTGACCCTGCTGGGCCTGCTGGGCGCAGGTGCCAGCCTGAGGCCCCGCA
  AGCTGGACTTCTTCCGCAGCGAGAAAGAGCTGAACCACCTGGCTGTGGATGAGGCCTCAGGCGTGGTGTA
  CCTGGGGGCGGTGAATGCCCTCTACCAGCTGGATGCGAAGCTGCAGCTGGAGCAGCAGGTGGCCACGGGC
  CCGGCCCTGGACAACAAGAAGTGCACGCCGCCCATCGAGGCCAGCCAGTGCCATGAGGCTGAGATGACTG
  ACAATGTCAACCAGCTGCTGCTGCTCGACCCTCCCAGGAAGCGCCTGGTGGAGTGCGGCAGCCTCTTCAA
  GGGCATCTGCGCTCTGCGCGCCCTGAGCAACATCTCCCTCCGCCTGTTCTACGAGGACGGCAGCGGGGAG
  AAGTCTTTCGTGGCCAGCAATGATGAGGGCGTGGCCACAGTGGGGCTGGTGAGCTCCACGGGTCCTGGTG
  GTGACCGCGTGCTGTTTGTGGGCAAAGGCAATGGGCCACACGACAACGGCATCATCGTGAGCACTCGGCT
  GTTGGACCGGACTGACAGCAGGGAGGCCTTTGAAGCCTACACGGACCACGCCACCTACAAGGCCGGCTAC
  CTGTCCACCAACACACAGCAGTTCGTGGCGGCCTTCGAGGACGGCCCCTACGTCTTCTTTGTCTTCAACC
  AGCAGGACAAGCACCCGGCCCGGAACCGCACGCTGCTGGCACGCATGTGCAGAGAAGACCCCAACTACTA
  CTCCTACCTGGAGATGGACCTGCAGTGCCGGGACCCCGACATCCACGCCGCTGCCTTTGGCACCTGCCTG
  GCCGCCTCCGTGGCTGCGCCTGGCTCTGGCAGGGTGCTATATGCTGTCTTCAGCAGAGACAGCCGGAGCA
  GTGGGGGGCCCGGTGCGGGCCTCTGCCTGTTCCCGCTGGACAAGGTGCACGCCAAGATGGAGGCCAACCG
  CAACGCCTGTTACACAGGCACCCGGGAGGCCCGTGACATCTTCTACAAGCCCTTCCACGGCGATATCCAG
  TGCGGCGGCCACGCGCCGGGCTCCAGCAAGAGCTTCCCATGTGGCTCGGAGCACCTGCCCTACCCGCTGG
  GCAGCCGCGACGGGCTCAGAGGCACAGCCGTGCTGCAGCGTGGAGGCCTGAACCTCACGGCCGTGACGGT
  CGCCGCCGAGAACAACCACACTGTTGCTTTTCTGGGCACCTCTGATGGCCGGATCCTCAAGGTGTACCTC
  ACCCCAGATGGCACCTCCTCAGAGTACGACTCTATCCTTGTGGAGATAAACAAGAGAGTCAAGCGCGACC
  TGGTACTGTCTGGAGACCTGGGCAGCCTGTACGCCATGACCCAGGACAAGGTGTTCCGGCTGCCGGTGCA
  GGAGTGCCTGAGCTACCCGACCTGCACCCAGTGCCGCGACTCCCAGGACCCCTACTGCGGCTGGTGCGTC
  GTCGAGGGACGATGCACCCGGAAGGCCGAGTGTCCGCGGGCCGAGGAGGCCAGCCACTGGCTGTGGAGCC
  GAAGCAAGTCCTGCGTGGCCGTCACCAGCGCCCAGCCACAGAACATGAGCCGGCGGGCCCAGGGGGAGGT
  GCAGCTGACCGTCAGCCCCCTCCCTGCCCTGAGCGAGGAGGACGAGTTGCTGTGCCTTTTTGGGGAGTCG
  CCGCCACACCCCGCCCGCGTGGAGGGCGAGGCCGTCATCTGCAACTCCCCAAGCAGCATCCCCGTCACAC
  CGCCAGGCCAGGACCACGTGGCCGTGACCATCCAGCTCCTCCTTAGACGAGGCAACATCTTCCTCACGTC
  CTACCAGTACCCCTTCTACGACTGCCGCCAGGCCATGAGCCTGGAGGAGAACCTGCCGTGCATCTCCTGC
  GTGAGCAACCGCTGGACCTGCCAGTGGGACCTGCGCTACCACGAGTGCCGGGAGGCTTCGCCCAACCCTG
  AGGACGGCATCGTCCGTGCCCACATGGAGGACAGCTGTCCCCAGTTCCTGGGACCCAGCCCCCTGGTGAT
  CCCCATGAACCACGAGACAGATGTGAACTTCCAGGGCAAGAACCTGGACACCGTGAAGGGTTCCTCCCTG
  CACGTGGGCAGTGACTTGCTCAAGTTCATGGAGCCGGTGACCATGCAGGAATCTGGGACCTTCGCCTTTC
  GGACCCCAAAGCTGTCCCACGATGCCAACGAGACGCTGCCCCTGCACCTCTACGTCAAGTCTTACGGCAA
  GAATATCGACAGCAAGCTCCATGTGACCCTCTACAACTGCTCCTTTGGCCGCAGCGACTGCAGCCTGTGC
  CGGGCCGCTAACCCCGACTACAGGTGTGCGTGGTGCGGGGGCCAGAGCAGGTGCGTGTATGAGGCCCTGT
  GCAACACCACCTCCGAGTGCCCGCCGCCCGTCATCACCAGGATCCAGCCTGAGACGGGCCCCCTGGGTGG
  GGGCATCCGCATCACCATCCTGGGGTCCAATTTGGGCGTCCAAGCAGGGGACATCCAGAGGATCTCTGTG
  GCCGGCCGGAACTGCTCCTTTCAGCCGGAACGTTACTCCGTGTCCACCCGGATCGTGTGTGTGATCGAGG
  CTGCGGAGACGCCTTTCACGGGGGGTGTCGAGGTGGACGTCTTCGGGAAACTGGGCCGTTCGCCTCCCAA
  TGTCCAGTTCACCTTCCAACAGCCCAAGCCTCTCAGTGTGGAGCCGCAGCAGGGACCGCAGGCGGGCGGC
  ACCACACTGACCATCCACGGCACCCACCTGGACACGGGCTCCCAGGAGGACGTGCGGGTGACCCTCAACG
  GCGTCCCGTGTAAAGTGACGAAGTTTGGGGCGCAGCTCCAGTGTGTCACTGGCCCCCAGGCGACACGGGG
  CCAGATGCTTCTGGAGGTCTCCTACGGGGGGTCCCCCGTGCCCAACCCCGGCATCTTCTTCACCTACCGC
  GAAAACCCCGTACTGCGAGCCTTCGAGCCGCTACGAAGCTTTGCCAGTGGTGGCCGCAGCATCAACGTCA
  CGGGTCAGGGCTTCAGCCTGATCCAGAGGTTTGCCATGGTGGTCATCGCGGAGCCCCTGCAGTCCTGGCA
  GCCGCCGCGGGAGGCTGAATCCCTGCAGCCCATGACGGTGGTGGGTACAGACTACGTGTTCCACAATGAC
  ACCAAGGTCGTCTTCCTGTCCCCGGCTGTGCCTGAGGAGCCAGAGGCCTACAACCTCACGGTGCTGATCG
  AGATGGACGGGCACCGTGCCCTGCTCAGAACAGAGGCCGGGGCCTTCGAGTACGTGCCTGACCCCACCTT
  TGAGAACTTCACAGGTGGCGTCAAGAAGCAGGTCAACAAGCTCATCCACGCCCGGGGCACCAATCTGAAC
  AAGGCGATGACGCTGCAGGAGGCCGAGGCCTTCGTGGGTGCCGAGCGCTGCACCATGAAGACGCTGACGG
  AGACCGACCTGTACTGTGAGCCCCCGGAGGTGCAGCCCCCGCCCAAGCGGCGGCAGAAACGAGACACCAC
  ACACAACCTGCCCGAGTTCATTGTGAAGTTCGGCTCTCGCGAGTGGGTGCTGGGCCGCGTGGAGTACGAC
  ACACGGGTGAGCGACGTGCCGCTCAGCCTCATCTTGCCGCTGGTCATCGTGCCCATGGTGGTCGTCATCG
  CGGTGTCTGTCTACTGCTACTGGAGGAAGAGCCAGCAGGCCGAACGAGAGTATGAGAAGATCAAGTCCCA
  GCTGGAGGGCCTGGAGGAGAGCGTGCGGGACCGCTGCAAGAAGGAATTCACAGACCTGATGATCGAGATG
  GAGGACCAGACCAACGACGTGCACGAGGCCGGCATCCCCGTGCTGGACTACAAGACCTACACCGACCGCG
  TCTTCTTCCTGCCCTCCAAGGACGGCGACAAGGACGTGATGATCACCGGCAAGCTGGACATCCCTGAGCC
  GCGGCGGCCGGTGGTGGAGCAGGCCCTCTACCAGTTCTCCAACCTGCTGAACAGCAAGTCTTTCCTCATC
  AATTTCATCCACACCCTGGAGAACCAGCGGGAGTTCTCGGCCCGCGCCAAGGTCTACTTCGCGTCCCTGC
  TGACGGTGGCGCTGCACGGGAAACTGGAGTACTACACGGACATCATGCACACGCTCTTCCTGGAGCTCCT
  GGAGCAGTACGTGGTGGCCAAGAACCCCAAGCTGATGCTGCGCAGGTCTGAGACTGTGGTGGAGAGGATG
  CTGTCCAACTGGATGTCCATCTGCCTGTACCAGTACCTCAAGGACAGTGCCGGGGAGCCCCTGTACAAGC
  TCTTCAAGGCCATCAAACATCAGGTGGAAAAGGGCCCGGTGGATGCGGTACAGAAGAAGGCCAAGTACAC
  TCTCAACGACACGGGGCTGCTGGGGGATGATGTGGAGTACGCACCCCTGACGGTGAGCGTGATCGTGCAG
  GACGAGGGAGTGGACGCCATCCCGGTGAAGGTCCTCAACTGTGACACCATCTCCCAGGTCAAGGAGAAGA
  TCATTGACCAGGTGTACCGTGGGCAGCCCTGCTCCTGCTGGCCCAGGCCAGACAGCGTGGTCCTGGAGTG
  GCGTCCGGGCTCCACAGCGCAGATCCTGTCGGACCTGGACCTGACGTCACAGCGGGAGGGCCGGTGGAAG
  CGCGTCAACACCCTTATGCACTACAATGTCCGGGATGGAGCCACCCTCATCCTGTCCAAGGTGGGGGTCT
  CCCAGCAGCCGGAGGACAGCCAGCAGGACCTGCCTGGGGAGCGCCATGCCCTCCTGGAGGAGGAGAACCG
  GGTGTGGCACCTGGTGCGGCCGACCGACGAGGTGGACGAGGGCAAGTCCAAGAGAGGCAGCGTGAAAGAG
  AAGGAGCGGACGAAGGCCATCACCGAGATCTACCTGACGCGGCTGCTCTCAGTCAAGGGCACACTGCAGC
  AGTTTGTGGACAACTTCTTCCAGAGCGTGCTGGCGCCTGGGCACGCGGTGCCACCTGCAGTCAAGTACTT
  CTTCGACTTCCTGGACGAGCAGGCAGAGAAGCACAACATCCAGGATGAAGACACCATCCACATCTGGAAG
  ACGAACAGCTTACCGCTCCGGTTCTGGGTGAACATCCTCAAGAACCCCCACTTCATCTTTGACGTGCATG
  TCCACGAGGTGGTGGACGCCTCGCTGTCAGTCATCGCGCAGACCTTCATGGATGCCTGCACGCGCACGGA
  GCATAAGCTGAGCCGCGATTCTCCCAGCAACAAGCTGCTGTACGCCAAGGAGATCTCCACCTACAAGAAG
  ATGGTGGAGGATTACTACAAGGGGATCCGGCAGATGGTGCAGGTCAGCGACCAGGACATGAACACACACC
  TGGCAGAGATTTCCCGGGCGCACACGGACTCCTTGAACACCCTCGTGGCACTCCACCAGCTCTACCAATA
  CACGCAGAAGTACTATGACGAGATCATCAATGCCTTGGAGGAGGATCCTGCCGCCCAGAAGATGCAGCTG
  GCCTTCCGCCTGCAGCAGATTGCCGCTGCACTGGAGAACAAGGTCACTGACCTC
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC213651 representing NM_012401
  Red=Cloning site Green=Tags(s)
  
  MALQLWALTLLGLLGAGASLRPRKLDFFRSEKELNHLAVDEASGVVYLGAVNALYQLDAKLQLEQQVATG
  PALDNKKCTPPIEASQCHEAEMTDNVNQLLLLDPPRKRLVECGSLFKGICALRALSNISLRLFYEDGSGE
  KSFVASNDEGVATVGLVSSTGPGGDRVLFVGKGNGPHDNGIIVSTRLLDRTDSREAFEAYTDHATYKAGY
  LSTNTQQFVAAFEDGPYVFFVFNQQDKHPARNRTLLARMCREDPNYYSYLEMDLQCRDPDIHAAAFGTCL
  AASVAAPGSGRVLYAVFSRDSRSSGGPGAGLCLFPLDKVHAKMEANRNACYTGTREARDIFYKPFHGDIQ
  CGGHAPGSSKSFPCGSEHLPYPLGSRDGLRGTAVLQRGGLNLTAVTVAAENNHTVAFLGTSDGRILKVYL
  TPDGTSSEYDSILVEINKRVKRDLVLSGDLGSLYAMTQDKVFRLPVQECLSYPTCTQCRDSQDPYCGWCV
  VEGRCTRKAECPRAEEASHWLWSRSKSCVAVTSAQPQNMSRRAQGEVQLTVSPLPALSEEDELLCLFGES
  PPHPARVEGEAVICNSPSSIPVTPPGQDHVAVTIQLLLRRGNIFLTSYQYPFYDCRQAMSLEENLPCISC
  VSNRWTCQWDLRYHECREASPNPEDGIVRAHMEDSCPQFLGPSPLVIPMNHETDVNFQGKNLDTVKGSSL
  HVGSDLLKFMEPVTMQESGTFAFRTPKLSHDANETLPLHLYVKSYGKNIDSKLHVTLYNCSFGRSDCSLC
  RAANPDYRCAWCGGQSRCVYEALCNTTSECPPPVITRIQPETGPLGGGIRITILGSNLGVQAGDIQRISV
  AGRNCSFQPERYSVSTRIVCVIEAAETPFTGGVEVDVFGKLGRSPPNVQFTFQQPKPLSVEPQQGPQAGG
  TTLTIHGTHLDTGSQEDVRVTLNGVPCKVTKFGAQLQCVTGPQATRGQMLLEVSYGGSPVPNPGIFFTYR
  ENPVLRAFEPLRSFASGGRSINVTGQGFSLIQRFAMVVIAEPLQSWQPPREAESLQPMTVVGTDYVFHND
  TKVVFLSPAVPEEPEAYNLTVLIEMDGHRALLRTEAGAFEYVPDPTFENFTGGVKKQVNKLIHARGTNLN
  KAMTLQEAEAFVGAERCTMKTLTETDLYCEPPEVQPPPKRRQKRDTTHNLPEFIVKFGSREWVLGRVEYD
  TRVSDVPLSLILPLVIVPMVVVIAVSVYCYWRKSQQAEREYEKIKSQLEGLEESVRDRCKKEFTDLMIEM
  EDQTNDVHEAGIPVLDYKTYTDRVFFLPSKDGDKDVMITGKLDIPEPRRPVVEQALYQFSNLLNSKSFLI
  NFIHTLENQREFSARAKVYFASLLTVALHGKLEYYTDIMHTLFLELLEQYVVAKNPKLMLRRSETVVERM
  LSNWMSICLYQYLKDSAGEPLYKLFKAIKHQVEKGPVDAVQKKAKYTLNDTGLLGDDVEYAPLTVSVIVQ
  DEGVDAIPVKVLNCDTISQVKEKIIDQVYRGQPCSCWPRPDSVVLEWRPGSTAQILSDLDLTSQREGRWK
  RVNTLMHYNVRDGATLILSKVGVSQQPEDSQQDLPGERHALLEEENRVWHLVRPTDEVDEGKSKRGSVKE
  KERTKAITEIYLTRLLSVKGTLQQFVDNFFQSVLAPGHAVPPAVKYFFDFLDEQAEKHNIQDEDTIHIWK
  TNSLPLRFWVNILKNPHFIFDVHVHEVVDASLSVIAQTFMDACTRTEHKLSRDSPSNKLLYAKEISTYKK
  MVEDYYKGIRQMVQVSDQDMNTHLAEISRAHTDSLNTLVALHQLYQYTQKYYDEIINALEEDPAAQKMQL
  AFRLQQIAAALENKVTDL
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_012401
• ORF Size: 5514 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_012401.2, NM_012401.3, NP_036533.2
• RefSeq Size: 6369
• RefSeq ORF: 5517
• Locus ID: 23654
• Protein Families: Druggable Genome
• Protein Pathways: Axon guidance
• MW: 204.9 kDa
• Gene Summary: Members of the B class of plexins, such as PLXNB2 are transmembrane receptors that participate in axon guidance and cell migration in response to semaphorins (Perrot et al. (2002) [PubMed 12183458]). [supplied by OMIM, Mar 2008]