ECE2 (NM_001100120) Human Tagged ORF Clone

CAT#: RC214966L4

Lenti-ORF clone of ECE2 (mGFP-tagged)-Human endothelin converting enzyme 2 (ECE2), transcript variant 4

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: mGFP
• Symbol: ECE2
• Synonyms: EEF1AKMT4
• Vector: pLenti-C-mGFP-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC214966).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_001100120
• ORF Size: 2433 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001100120.1, NP_001093590.1
• RefSeq Size: 3387
• RefSeq ORF: 2436
• Locus ID: 9718
• Protein Families: Druggable Genome, Protease, Transmembrane
• MW: 91 kDa
• Gene Summary: This gene encodes a member of the M13 family, which includes type 2 integral membrane metallopeptidases. The encoded enzyme is a membrane-bound zinc-dependent metalloprotease. The enzyme catalyzes the cleavage of big endothelin to produce the vasoconstrictor endothelin-1, and plays a role in the processing of several neuroendocrine peptides. It may also have methyltransferase activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]