DPP8 (NM_017743) Human Tagged ORF Clone

CAT#: RC215204L3

Lenti-ORF clone of DPP8 (Myc-DDK-tagged)-Human dipeptidyl-peptidase 8 (DPP8), transcript variant 2

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: DPP8
• Synonyms: DP8; DPRP-1; DPRP1; MST097; MSTP097; MSTP135; MSTP141
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC215204).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_017743
• ORF Size: 2346 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_017743.4, NP_060213.2
• RefSeq Size: 3796
• RefSeq ORF: 2349
• Locus ID: 54878
• Domains: DPPIV_N_term
• Protein Families: Druggable Genome, Protease, Transmembrane
• MW: 89.9 kDa
• Gene Summary: This gene encodes a member of the peptidase S9B family, a small family of dipeptidyl peptidases that are able to cleave peptide substrates at a prolyl bond. The encoded protein shares similarity with dipeptidyl peptidase IV in that it is ubiquitously expressed, and hydrolyzes the same substrates. These similarities suggest that, like dipeptidyl peptidase IV, this protein may play a role in T-cell activation and immune function. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]