Neurexin 1 (NRXN1) (NM_138735) Human Tagged ORF Clone
CAT#: RC215381
- TrueORF®
NRXN1 (Myc-DDK-tagged)-Human neurexin 1 (NRXN1), transcript variant beta
"NM_138735" in other vectors (6)
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | NRXN1 |
Synonyms | Hs.22998; PTHSL2; SCZD17 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RC215381 representing NM_138735
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGTACCAGAGGATGCTCCGGTGCGGCGCCGAGCTGGGCTCGCCCGGGGGCGGCGGCGGCGGCGGCGGCG GCGGCGGCGCAGGGGGGCGCCTGGCCCTGCTTTGGATAGTCCCGCTCACCCTCAGCGGCCTCCTAGGAGT GGCGTGGGGGGCATCCAGTTTGGGAGCGCACCACATCCACCATTTCCATGGCAGCAGCAAGCATCATTCA GTGCCTATTGCAATCTACAGGTCACCGGCATCCTTGCGAGGCGGACACGCTGGGACGACATATATCTTTA GCAAAGGTGGTGGACAAATCACGTATAAGTGGCCTCCTAATGACCGACCCAGTACACGAGCAGACAGACT GGCCATAGGTTTTAGCACTGTTCAGAAAGAAGCCGTATTGGTGCGAGTGGACAGTTCTTCAGGCTTGGGT GACTACCTAGAACTGCATATACACCAGGGAAAAATTGGAGTTAAGTTTAATGTTGGGACAGATGACATCG CCATTGAAGAATCCAATGCAATCATTAATGATGGGAAATACCATGTAGTTCGTTTCACGAGGAGTGGTGG CAATGCCACGTTGCAGGTGGACAGCTGGCCAGTGATCGAGCGCTACCCTGCAGGGCGTCAGCTCACAATC TTCAATAGCCAAGCAACCATAATAATTGGCGGGAAAGAGCAGGGCCAGCCCTTCCAGGGCCAGCTCTCTG GGCTGTACTACAATGGCTTGAAAGTTCTGAATATGGCAGCCGAAAACGATGCCAACATCGCCATAGTGGG AAATGTGAGACTGGTTGGTGAAGTGCCTTCCTCTATGACAACTGAGTCAACAGCCACTGCCATGCAATCA GAGATGTCCACATCAATTATGGAGACTACCACGACCCTGGCTACTAGCACAGCCAGAAGAGGAAAGCCCC CGACAAAAGAACCCATTAGCCAGACCACAGATGACATCCTTGTGGCCTCAGCAGAGTGTCCCAGCGATGA TGAGGACATTGACCCCTGTGAGCCGAGCTCAGGTGGGTTAGCCAACCCAACCCGAGCAGGCGGCAGAGAG CCGTATCCAGGCTCAGCAGAAGTGATCCGGGAGTCCAGCAGCACCACGGGTATGGTCGTTGGGATAGTAG CCGCTGCCGCCCTGTGCATCCTTATCCTCCTCTATGCCATGTACAAGTACAGAAACCGGGATGAAGGCTC ATACCATGTGGACGAGAGTCGAAACTACATCAGTAACTCAGCACAGTCCAATGGGGCTGTTGTAAAGGAG AAACAACCCAGCAGTGCGAAAAGCTCCAACAAAAATAAGAAAAACAAGGATAAAGAGTATTATGTC ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC215381 representing NM_138735
Red=Cloning site Green=Tags(s) MYQRMLRCGAELGSPGGGGGGGGGGGAGGRLALLWIVPLTLSGLLGVAWGASSLGAHHIHHFHGSSKHHS VPIAIYRSPASLRGGHAGTTYIFSKGGGQITYKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGLG DYLELHIHQGKIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGRQLTI FNSQATIIIGGKEQGQPFQGQLSGLYYNGLKVLNMAAENDANIAIVGNVRLVGEVPSSMTTESTATAMQS EMSTSIMETTTTLATSTARRGKPPTKEPISQTTDDILVASAECPSDDEDIDPCEPSSGGLANPTRAGGRE PYPGSAEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYISNSAQSNGAVVKE KQPSSAKSSNKNKKNKDKEYYV TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_138735 |
ORF Size | 1326 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_138735.1, NM_138735.2, NM_138735.3, NM_138735.4, NP_620072.1 |
RefSeq Size | 3712 |
RefSeq ORF | 1329 |
Locus ID | 9378 |
Domains | LamG |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Cell adhesion molecules (CAMs) |
MW | 42.1 kDa |
Gene Summary | This gene encodes a single-pass type I membrane protein that belongs to the neurexin family. Neurexins are cell-surface receptors that bind neuroligins to form Ca(2+)-dependent neurexin/neuroligin complexes at synapses in the central nervous system. This complex is required for efficient neurotransmission and is involved in the formation of synaptic contacts. Three members of this gene family have been studied in detail and are estimated to generate over 3,000 variants through the use of two alternative promoters (alpha and beta) and extensive alternative splicing in each family member. Recently, a third promoter (gamma) was identified for this gene in the 3' region. Mutations in this gene are associated with Pitt-Hopkins-like syndrome-2 and may contribute to susceptibility to schizophrenia. [provided by RefSeq, Aug 2016] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC120579 | NRXN1 (untagged)-Human neurexin 1 (NRXN1), transcript variant beta |
USD 740.00 |
|
RG215381 | NRXN1 (GFP-tagged) - Human neurexin 1 (NRXN1), transcript variant beta |
USD 460.00 |
|
RC215381L1 | Lenti-ORF clone of NRXN1 (Myc-DDK-tagged)-Human neurexin 1 (NRXN1), transcript variant beta |
USD 768.00 |
|
RC215381L2 | Lenti-ORF clone of NRXN1 (mGFP-tagged)-Human neurexin 1 (NRXN1), transcript variant beta |
USD 620.00 |
|
RC215381L3 | Lenti-ORF clone of NRXN1 (Myc-DDK-tagged)-Human neurexin 1 (NRXN1), transcript variant beta |
USD 620.00 |
|
RC215381L4 | Lenti-ORF clone of NRXN1 (mGFP-tagged)-Human neurexin 1 (NRXN1), transcript variant beta |
USD 620.00 |
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