ASH2L (NM_004674) Human Tagged ORF Clone

CAT#: RC215552L2

Lenti ORF clone of Human ash2 (absent, small, or homeotic)-like (Drosophila) (ASH2L), transcript variant 1, mGFP tagged

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: mGFP
• Symbol: ASH2L
• Synonyms: ASH2; ASH2L1; ASH2L2; Bre2
• Vector: pLenti-C-mGFP
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC215552).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_004674
• ORF Size: 1884 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_004674.1, NP_004665.1
• RefSeq Size: 2381
• RefSeq ORF: 1887
• Locus ID: 9070
• Domains: SPRY
• Protein Families: Druggable Genome, Transcription Factors
• MW: 68.5 kDa
• Gene Summary: Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis. [UniProtKB/Swiss-Prot Function]