MRVI1 (NM_001100163) Human Tagged ORF Clone
CAT#: RC215686
- TrueORF®
MRVI1 (Myc-DDK-tagged)-Human murine retrovirus integration site 1 homolog (MRVI1), transcript variant 3
"NM_001100163" in other vectors (4)
Product Images
![](https://cdn.origene.com/img/defaults-img-expression-plasmids.jpg)
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | MRVI1 |
Synonyms | IRAG; JAW1L |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RC215686 representing NM_001100163
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC CTGACTGGGGATGCCACTTCACCAGAAGGAGAAACCGACAAAAACCTGGCCAACAGAGTTCACAGTCCCC ACAAGAGGCTTTCTCACCGACACTTGAAGGTGTCCACTGCCTCCCTGACATCTGTGGACCCCGCGGGGCA CATCATTGACCTGGTGAATGACCAGCTGCCAGACATCAGCATCTCAGAGGAGGACAAGAAGAAAAACCTG GCGCTGCTGGAAGAAGCCAAGTTGGTGAGTGAGCGATTCCTGACCCGCCGTGGGAGGAAGTCCAGGAGCA GCCCCGGAGACTCCCCATCAGCTGTTTCCCCGAACCTCAGCCCCAGCGCTTCTCCTACATCCTCTCGGAG CAACTCACTTACAGTCCCCACCCCGCCAGGTTTGGATGTGTGCAGTGGCCCGCCATCCCCTCTGCCTGGA GCACCACCACAGAAGGGGGATGAGGCCGACGTCTCTTCACCTCACCCTGGCGAGCCTAACGTCCCCAAAG GGCTAGCTGACAGGAAGCAGAATGACCAGAGGAAAGTGTCTCAGGGCAGGCTGGCTCCTCGTCCTCCTCC AGTTGAGAAGTCCAAAGAGATTGCAATAGAACAAAAGGAAAACTTCGATCCCCTCCAGTACCCCGAGACC ACACCCAAAGGCCTAGCTCCTGTTACAAACAGCAGTGGGAAAATGGCCCTGAACAGCCCTCAGCCTGGCC CCGTGGAGAGCGAGCTGGGGAAGCAGCTCTTGAAAACGGGCTGGGAGGGCAGCCCTCTGCCGAGAAGTCC AACCCAGGATGCGGCAGGAGTGGGTCCCCCAGCCTCCCAGGGGAGAGGCCCAGCTGGAGAGCCGATGGGG CCCGAGGCTGGCTCCAAAGCTGAGCTTCCACCCACTGTGTCCCGGCCCCCGCTGCTGCGAGGGCTCTCCT GGGACAGTGGCCCTGAAGAACCTGGCCCCCGGCTGCAGAAAGTGCTTGCCAAGCTGCCACTGGCAGAGGA AGAAAAGCGTTTTGCAGGCAAGGCCGGCGGCAAGCTGGCCAAGGCCCCTGGTCTCAAAGACTTTCAGATA CAAGTGCAGCCCGTGCGGATGCAGAAACTGACCAAGCTCCGAGAGGAGCACATCCTGATGAGAAATCAGA ACTTAGTGGGGCTCAAGCTTCCAGACCTTAGTGAAGCAGCTGAGCAGGAAAAAGGGCTTCCTTCTGAACT CTCCCCAGCTATTGAGGAAGAAGAGTCAAAGAGTGGCTTAGATGTCATGCCTAATATTTCTGATGTGCTG CTGCGCAAACTGCGGGTCCACAGGAGTCTCCCTGGAAGTGCCCCTCCACTCACTGAAAAGGAAGTTGAGA ACGTGTTTGTGCAACTGTCCTTGGCCTTTAGAAATGACAGCTACACTCTGGAATCTAGAATTAACCAGGC TGAAAGGGAACGCAACCTGACAGAGGAGAACACTGAGAAAGAACTGGAAAACTTCAAAGCTTCCATTACG TCCTCAGCTTCACTCTGGCACCACTGTGAGCACCGGGAAACCTACCAGAAGTTGCTGGAGGACATCGCTG TCCTGCACCGCCTGGCTGCCCGCCTCTCCAGCCGAGCTGAGGTGGTAGGCGCCGTCCGCCAGGAAAAGCG CATGTCGAAAGCAACGGAAGTGATGATGCAGTATGTGGAGAATCTAAAGAGGACGTATGAGAAGGACCAT GCGGAGCTCATGGAGTTTAAAAAGCTTGCAAATCAGAATTCAAGCCGCAGCTGTGGCCCCTCTGAAGATG GGGTCCCTCGCACGGCACGGTCCATGTCCCTCACGCTGGGAAAGAATATGCCTCGCCGGAGGGTCAGCGT TGCTGTGGTTCCTAAGTTTAATGCCCTGAATCTGCCTGGCCAAACTCCCAGCTCATCATCCATTCCCTCC TTACCAGCCTTGTCGGAATCACCCAATGGGAAAGGCAGCCTACCTGTCACTTCAGCACTGCCTGCACTTT TGGAAAATGGAAAGACAAATGGGGACCCAGATTGTGAAGCCTCTGCTCCTGCGCTGACCCTGAGCTGCCT GGAGGAGCTTAGTCAGGAGACCAAGGCCAGGATGGAGGAAGAAGCCTACAGCAAGGGATTCCAAGAAGGT CTAAAGAAGACCAAAGAACTTCAAGACCTGAAGGAGGAGGAGGAAGAACAGAAGAGTGAGAGTCCTGAGG AACCTGAAGAGGTAGAAGAAACTGAGGAAGAGGAAAAGGGCCCAAGAAGCAGCAAACTTGAAGAATTGGT CCATTTCTTACAAGTCATGTATCCCAAACTGTGTCAGCACTGGCAAGTGATCTGGATGATGGCTGCAGTG ATGCTGGTCTTGACTGTTGTGCTGGGGCTCTACAATTCCTATAACTCTTGTGCAGAGCAGGCTGATGGGC CCCTTGGAAGATCCACTTGCTCGGCAGCCCAGAGGGACTCCTGGTGGAGCTCAGGACTCCAGCATGAGCA GCCTACAGAGCAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC215686 representing NM_001100163
Red=Cloning site Green=Tags(s) LTGDATSPEGETDKNLANRVHSPHKRLSHRHLKVSTASLTSVDPAGHIIDLVNDQLPDISISEEDKKKNL ALLEEAKLVSERFLTRRGRKSRSSPGDSPSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSPLPG APPQKGDEADVSSPHPGEPNVPKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIAIEQKENFDPLQYPET TPKGLAPVTNSSGKMALNSPQPGPVESELGKQLLKTGWEGSPLPRSPTQDAAGVGPPASQGRGPAGEPMG PEAGSKAELPPTVSRPPLLRGLSWDSGPEEPGPRLQKVLAKLPLAEEEKRFAGKAGGKLAKAPGLKDFQI QVQPVRMQKLTKLREEHILMRNQNLVGLKLPDLSEAAEQEKGLPSELSPAIEEEESKSGLDVMPNISDVL LRKLRVHRSLPGSAPPLTEKEVENVFVQLSLAFRNDSYTLESRINQAERERNLTEENTEKELENFKASIT SSASLWHHCEHRETYQKLLEDIAVLHRLAARLSSRAEVVGAVRQEKRMSKATEVMMQYVENLKRTYEKDH AELMEFKKLANQNSSRSCGPSEDGVPRTARSMSLTLGKNMPRRRVSVAVVPKFNALNLPGQTPSSSSIPS LPALSESPNGKGSLPVTSALPALLENGKTNGDPDCEASAPALTLSCLEELSQETKARMEEEAYSKGFQEG LKKTKELQDLKEEEEEQKSESPEEPEEVEETEEEEKGPRSSKLEELVHFLQVMYPKLCQHWQVIWMMAAV MLVLTVVLGLYNSYNSCAEQADGPLGRSTCSAAQRDSWWSSGLQHEQPTEQ TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
![]() |
ACCN | NM_001100163 |
ORF Size | 2463 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001100163.1, NM_001100163.2, NP_001093633.1 |
RefSeq Size | 6323 |
RefSeq ORF | 2466 |
Locus ID | 10335 |
Protein Families | Transmembrane |
Protein Pathways | Vascular smooth muscle contraction |
MW | 89.7 kDa |
Gene Summary | This gene is similar to a putative mouse tumor suppressor gene (Mrvi1) that is frequently disrupted by mouse AIDS-related virus (MRV). The encoded protein, which is found in the membrane of the endoplasmic reticulum, is similar to Jaw1, a lymphoid-restricted protein whose expression is down-regulated during lymphoid differentiation. This protein is a substrate of cGMP-dependent kinase-1 (PKG1) that can function as a regulator of IP3-induced calcium release. Studies in mouse suggest that MRV integration at Mrvi1 induces myeloid leukemia by altering the expression of a gene important for myeloid cell growth and/or differentiation, and thus this gene may function as a myeloid leukemia tumor suppressor gene. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene, and alternative translation start sites, including a non-AUG (CUG) start site, are used. [provided by RefSeq, May 2011] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC316838 | MRVI1 (untagged)-Human murine retrovirus integration site 1 homolog (MRVI1), transcript variant 3 |
USD 760.00 |
|
RG215686 | MRVI1 (GFP-tagged) - Human murine retrovirus integration site 1 homolog (MRVI1), transcript variant 3 |
USD 950.00 |
|
RC215686L3 | Lenti-ORF clone of MRVI1 (Myc-DDK-tagged)-Human murine retrovirus integration site 1 homolog (MRVI1), transcript variant 3 |
USD 1,060.00 |
|
RC215686L4 | Lenti-ORF clone of MRVI1 (mGFP-tagged)-Human murine retrovirus integration site 1 homolog (MRVI1), transcript variant 3 |
USD 1,060.00 |
{0} Product Review(s)
Be the first one to submit a review