CARD15 (NOD2) (NM_022162) Human Tagged ORF Clone
CAT#: RC215750L3
- LentiORF®
Lenti-ORF clone of NOD2 (Myc-DDK-tagged)-Human nucleotide-binding oligomerization domain containing 2 (NOD2)
"NM_022162" in other vectors (6)
Product Images
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | NOD2 |
Synonyms | ACUG; BLAU; BLAUS; CARD15; CD; CLR16.3; IBD1; NLRC2; NOD2B; PSORAS1; YAOS |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC215750).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_022162 |
ORF Size | 3120 bp |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_022162.1, NP_071445.1 |
RefSeq Size | 4485 |
RefSeq ORF | 3123 |
Locus ID | 64127 |
Protein Families | Druggable Genome |
Protein Pathways | NOD-like receptor signaling pathway |
MW | 115.1 kDa |
Gene Summary | This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2014] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC305010 | NOD2 (untagged)-Human nucleotide-binding oligomerization domain containing 2 (NOD2) |
USD 2,110.00 |
|
RC215750 | NOD2 (Myc-DDK-tagged)-Human nucleotide-binding oligomerization domain containing 2 (NOD2) |
USD 1,090.00 |
|
RG215750 | NOD2 (GFP-tagged) - Human nucleotide-binding oligomerization domain containing 2 (NOD2) |
USD 1,200.00 |
|
RC215750L1 | Lenti-ORF clone of NOD2 (Myc-DDK-tagged)-Human nucleotide-binding oligomerization domain containing 2 (NOD2) |
USD 1,596.00 |
|
RC215750L2 | Lenti-ORF clone of NOD2 (mGFP-tagged)-Human nucleotide-binding oligomerization domain containing 2 (NOD2) |
USD 1,290.00 |
|
RC215750L4 | Lenti-ORF clone of NOD2 (mGFP-tagged)-Human nucleotide-binding oligomerization domain containing 2 (NOD2) |
USD 1,290.00 |
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