SLC4A10 (NM_022058) Human Tagged ORF Clone

CAT#: RC216112L3

Lenti-ORF clone of SLC4A10 (Myc-DDK-tagged)-Human solute carrier family 4, sodium bicarbonate transporter, member 10 (SLC4A10), transcript variant 2

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: SLC4A10
• Synonyms: NBCn2; NCBE
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC216112).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_022058
• ORF Size: 3264 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_022058.3, NP_071341.2
• RefSeq Size: 5580
• RefSeq ORF: 3267
• Locus ID: 57282
• Domains: HCO3_cotransp
• Protein Families: Druggable Genome, Transmembrane
• MW: 122.6 kDa
• Gene Summary: This gene belongs to a small family of sodium-coupled bicarbonate transporters (NCBTs) that regulate the intracellular pH of neurons, the secretion of bicarbonate ions across the choroid plexus, and the pH of the brain extracellular fluid. The protein encoded by this gene was initially identified as a sodium-driven chloride bicarbonate exchanger (NCBE) though there is now evidence that its sodium/bicarbonate cotransport activity is independent of any chloride ion countertransport under physiological conditions. This gene is now classified as a member A10 of the SLC4 family of transmembrane solute carriers. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2010]