MAP3K12 (NM_006301) Human Tagged ORF Clone
CAT#: RC216463
- TrueORF®
MAP3K12 (Myc-DDK-tagged)-Human mitogen-activated protein kinase kinase kinase 12 (MAP3K12), transcript variant 2
"NM_006301" in other vectors (6)
Product Images
![](https://cdn.origene.com/img/defaults-img-expression-plasmids.jpg)
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | MAP3K12 |
Synonyms | DLK; MEKK12; MUK; ZPK; ZPKP1 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RC216463 representing NM_006301
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCTTGCCTCCATGAGACCCGAACACCCTCTCCTTCCTTTGGGGGCTTTGTGTCTACCCTAAGTGAGG CATCCATGCGCAAGCTGGACCCAGACACTTCTGACTGCACTCCCGAGAAGGACCTGACGCCTACCCATGT CCTGCAGCTACATGAGCAGGATGCAGGGGGCCCAGGGGGAGCAGCTGGGTCACCTGAGAGTCGGGCATCC AGAGTTCGAGCTGACGAGGTGCGACTGCAGTGCCAGAGTGGCAGTGGCTTCCTTGAGGGCCTCTTTGGCT GCCTGCGCCCTGTCTGGACCATGATTGGCAAAGCCTACTCCACTGAGCACAAGCAGCAGCAGGAAGACCT TTGGGAGGTCCCCTTTGAGGAAATCCTGGACCTGCAGTGGGTGGGCTCAGGGGCCCAGGGTGCTGTCTTC CTGGGGCGCTTCCACGGGGAGGAGGTGGCTGTGAAGAAGGTGCGAGACCTCAAAGAAACCGACATCAAGC ACTTGCGAAAGCTGAAGCACCCCAACATCATCACTTTCAAGGGTGTGTGCACCCAGGCTCCCTGCTACTG CATCCTCATGGAGTTCTGCGCCCAGGGCCAGCTGTATGAGGTACTGCGGGCTGGCCGCCCTGTCACCCCC TCCTTACTGGTTGACTGGTCCATGGGCATCGCTGGTGGCATGAACTACCTGCACCTGCACAAGATTATCC ACAGGGATCTCAAGTCACCCAACATGCTAATCACCTACGACGATGTGGTGAAGATCTCAGATTTTGGCAC TTCCAAGGAGCTGAGTGACAAGAGCACCAAGATGTCCTTTGCAGGGACAGTAGCCTGGATGGCCCCTGAG GTGATCCGCAATGAACCTGTGTCTGAGAAGGTCGACATCTGGTCCTTTGGCGTGGTGCTATGGGAACTGC TGACTGGTGAGATCCCCTACAAAGACGTAGATTCCTCAGCCATTATCTGGGGTGTGGGAAGCAACAGTCT CCATCTGCCCGTGCCCTCCAGTTGCCCAGATGGTTTCAAGATCCTGCTTCGCCAGTGCTGGAATAGCAAA CCACGAAATCGCCCATCATTCCGACAGATCCTGCTGCATCTGGACATTGCCTCAGCTGATGTACTCTCCA CACCCCAGGAGACTTACTTTAAGTCCCAGGCAGAGTGGCGGGAAGAAGTAAAACTGCACTTTGAAAAGAT TAAGTCAGAAGGGACCTGTCTGCACCGCCTAGAAGAGGAACTGGTGATGAGGAGGAGGGAGGAGCTCAGA CACGCCCTGGACATCAGGGAGCACTATGAAAGGAAGCTGGAGAGAGCCAACAACCTGTATATGGAACTTA ATGCCCTCATGTTGCAGCTGGAACTCAAGGAGAGGGAGCTGCTCAGGCGAGAGCAAGCTTTAGAGCGGAG GTGCCCAGGCCTGCTGAAGCCACACCCTTCCCGGGGCCTCCTGCATGGAAACACAATGGAGAAGCTTATC AAGAAGAGGAATGTGCCACAGAAGCTGTCACCCCATAGCAAAAGGCCAGATATCCTCAAGACGGAGTCTT TGCTCCCTAAACTAGATGCAGCCCTGAGTGGGGTGGGGCTTCCTGGGTGTCCTAAGGGCCCCCCCTCACC AGGACGGAGTCGCCGTGGCAAGACCCGTCACCGCAAGGCCAGCGCCAAGGGGAGCTGTGGGGACCTGCCT GGGCTTCGTACAGCTGTGCCACCCCATGAACCTGGAGGACCAGGAAGCCCAGGGGGCCTAGGAGGGGGAC CCTCAGCCTGGGAGGCCTGCCCTCCCGCCCTCCGTGGGCTTCATCATGACCTCCTGCTCCGCAAAATGTC TTCATCGTCCCCAGACCTGCTGTCAGCAGCACTAGGGTCCCGGGGCCGGGGGGCCACAGGCGGAGCTGGG GATCCTGGCTCACCACCTCCGGCCCGGGGTGACACCCCACCAAGTGAGGGCTCAGCCCCTGGCTCCACCA GCCCAGATTCACCTGGGGGAGCCAAAGGGGAACCACCTCCTCCAGTAGGGCCTGGTGAAGGTGTGGGGCT TCTGGGAACTGGAAGGGAAGGGACCTCAGGCCGGGGAGGAAGCCGGGCTGGGTCCCAGCACTTGACCCCA GCTGCACTGCTGTACAGGGCTGCCGTCACCCGAAGTCAGAAACGTGGCATCTCATCGGAAGAGGAGGAAG GAGAGGTAGACAGTGAAGTAGAGCTGACATCAAGCCAGAGGTGGCCTCAGAGCCTGAACATGCGCCAGTC ACTATCTACCTTCAGCTCAGAGAATCCATCAGATGGGGAGGAAGGCACAGCTAGTGAACCTTCCCCCAGT GGCACACCTGAAGTTGGCAGCACCAACACTGATGAGCGGCCAGATGAGCGGTCTGATGACATGTGCTCCC AGGGCTCAGAAATCCCACTGGACCCACCTCCTTCAGAGGTCATCCCTGGCCCTGAACCCAGCTCCCTGCC CATTCCACACCAGGAACTTCTCAGAGAGCGGGGCCCTCCCAATTCTGAGGACTCAGACTGTGACAGCACT GAATTGGACAACTCCAACAGCGTTGATGCCTTGCGGCCCCCAGCTTCCCTCCCTCCA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC216463 representing NM_006301
Red=Cloning site Green=Tags(s) MACLHETRTPSPSFGGFVSTLSEASMRKLDPDTSDCTPEKDLTPTHVLQLHEQDAGGPGGAAGSPESRAS RVRADEVRLQCQSGSGFLEGLFGCLRPVWTMIGKAYSTEHKQQQEDLWEVPFEEILDLQWVGSGAQGAVF LGRFHGEEVAVKKVRDLKETDIKHLRKLKHPNIITFKGVCTQAPCYCILMEFCAQGQLYEVLRAGRPVTP SLLVDWSMGIAGGMNYLHLHKIIHRDLKSPNMLITYDDVVKISDFGTSKELSDKSTKMSFAGTVAWMAPE VIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNSK PRNRPSFRQILLHLDIASADVLSTPQETYFKSQAEWREEVKLHFEKIKSEGTCLHRLEEELVMRRREELR HALDIREHYERKLERANNLYMELNALMLQLELKERELLRREQALERRCPGLLKPHPSRGLLHGNTMEKLI KKRNVPQKLSPHSKRPDILKTESLLPKLDAALSGVGLPGCPKGPPSPGRSRRGKTRHRKASAKGSCGDLP GLRTAVPPHEPGGPGSPGGLGGGPSAWEACPPALRGLHHDLLLRKMSSSSPDLLSAALGSRGRGATGGAG DPGSPPPARGDTPPSEGSAPGSTSPDSPGGAKGEPPPPVGPGEGVGLLGTGREGTSGRGGSRAGSQHLTP AALLYRAAVTRSQKRGISSEEEEGEVDSEVELTSSQRWPQSLNMRQSLSTFSSENPSDGEEGTASEPSPS GTPEVGSTNTDERPDERSDDMCSQGSEIPLDPPPSEVIPGPEPSSLPIPHQELLRERGPPNSEDSDCDST ELDNSNSVDALRPPASLPP TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_006301 |
ORF Size | 2577 bp |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_006301.1, NM_006301.2, NM_006301.3, NP_006292.2, NP_006292.3 |
RefSeq Size | 3541 |
RefSeq ORF | 2580 |
Locus ID | 7786 |
Domains | pkinase, TyrKc, S_TKc |
Protein Families | Druggable Genome, Protein Kinase |
Protein Pathways | MAPK signaling pathway |
MW | 93.7 kDa |
Gene Summary | This gene encodes a member of the serine/threonine protein kinase family. This kinase contains a leucine-zipper domain and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation. Alternatively spliced transcript variants encoding different proteins have been described. [provided by RefSeq, Jul 2010] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC310080 | MAP3K12 (untagged)-Human mitogen-activated protein kinase kinase kinase 12 (MAP3K12), transcript variant 2 |
USD 1,750.00 |
|
RG216463 | MAP3K12 (GFP-tagged) - Human mitogen-activated protein kinase kinase kinase 12 (MAP3K12), transcript variant 2 |
USD 1,060.00 |
|
RC216463L1 | Lenti-ORF clone of MAP3K12 (Myc-DDK-tagged)-Human mitogen-activated protein kinase kinase kinase 12 (MAP3K12), transcript variant 2 |
USD 1,160.00 |
|
RC216463L2 | Lenti-ORF clone of MAP3K12 (mGFP-tagged)-Human mitogen-activated protein kinase kinase kinase 12 (MAP3K12), transcript variant 2 |
USD 1,160.00 |
|
RC216463L3 | Lenti-ORF clone of MAP3K12 (Myc-DDK-tagged)-Human mitogen-activated protein kinase kinase kinase 12 (MAP3K12), transcript variant 2 |
USD 1,160.00 |
|
RC216463L4 | Lenti-ORF clone of MAP3K12 (mGFP-tagged)-Human mitogen-activated protein kinase kinase kinase 12 (MAP3K12), transcript variant 2 |
USD 1,160.00 |
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