ATG16L1 (NM_030803) Human Tagged ORF Clone

CAT#: RC216728L3

Lenti ORF clone of Human ATG16 autophagy related 16-like 1 (S. cerevisiae) (ATG16L1), transcript variant 1, Myc-DDK-tagged

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: ATG16L1
• Synonyms: APG16L; ATG16A; ATG16L; IBD10; WDR30
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC216728).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_030803
• ORF Size: 1821 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_030803.6, NP_110430.5
• RefSeq Size: 3411
• RefSeq ORF: 1824
• Locus ID: 55054
• Domains: WD40
• MW: 68.1 kDa
• Gene Summary: The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]