TMPRSS11D (NM_004262) Human Tagged ORF Clone

CAT#: RC217066L2

Lenti ORF clone of Human transmembrane protease, serine 11D (TMPRSS11D), mGFP tagged

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: mGFP
• Symbol: TMPRSS11D
• Synonyms: HAT
• Vector: pLenti-C-mGFP
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC217066).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_004262
• ORF Size: 1254 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_004262.2, NP_004253.1
• RefSeq Size: 2800
• RefSeq ORF: 1257
• Locus ID: 9407
• Protein Families: Druggable Genome, Protease, Secreted Protein, Transmembrane
• MW: 46.1 kDa
• Gene Summary: This gene encodes a trypsin-like serine protease released from the submucosal serous glands onto mucous membrane. It is a type II integral membrane protein and has 29-38% identity in the sequence of the catalytic region with human hepsin, enteropeptidase, acrosin, and mast cell tryptase. The noncatalytic region has little similarity to other known proteins. This protein may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions. [provided by RefSeq, Jul 2008]