VAV3 (NM_001079874) Human Tagged ORF Clone
CAT#: RC218352L4
- LentiORF®
Lenti ORF clone of Human vav 3 guanine nucleotide exchange factor (VAV3), transcript variant 2, mGFP tagged
"NM_001079874" in other vectors (6)
Product Images
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | mGFP |
Symbol | VAV3 |
Synonyms | FLJ40431 |
Vector | pLenti-C-mGFP-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC218352).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_001079874 |
ORF Size | 861 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001079874.1, NP_001073343.1 |
RefSeq Size | 3115 |
RefSeq ORF | 864 |
Locus ID | 10451 |
Protein Families | Druggable Genome |
Protein Pathways | B cell receptor signaling pathway, Chemokine signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, Leukocyte transendothelial migration, Natural killer cell mediated cytotoxicity, Regulation of actin cytoskeleton, T cell receptor signaling pathway |
MW | 32.4 kDa |
Gene Summary | This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC315719 | VAV3 (untagged)-Human vav 3 guanine nucleotide exchange factor (VAV3), transcript variant 2 |
USD 660.00 |
|
RC218352 | VAV3 (Myc-DDK-tagged)-Human vav 3 guanine nucleotide exchange factor (VAV3), transcript variant 2 |
USD 420.00 |
|
RG218352 | VAV3 (GFP-tagged) - Human vav 3 guanine nucleotide exchange factor (VAV3), transcript variant 2 |
USD 460.00 |
|
RC218352L1 | Lenti ORF clone of Human vav 3 guanine nucleotide exchange factor (VAV3), transcript variant 2, Myc-DDK-tagged |
USD 620.00 |
|
RC218352L2 | Lenti ORF clone of Human vav 3 guanine nucleotide exchange factor (VAV3), transcript variant 2, mGFP tagged |
USD 620.00 |
|
RC218352L3 | Lenti ORF clone of Human vav 3 guanine nucleotide exchange factor (VAV3), transcript variant 2, Myc-DDK-tagged |
USD 620.00 |
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