DMP1 (NM_004407) Human Tagged ORF Clone
CAT#: RC218741L3
- LentiORF®
Lenti ORF clone of Human dentin matrix acidic phosphoprotein 1 (DMP1), transcript variant 1, Myc-DDK-tagged
"NM_004407" in other vectors (6)
Product Images
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Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | DMP1 |
Synonyms | ARHP; ARHR; DMP-1 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC218741).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_004407 |
ORF Size | 1539 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_004407.1, NP_004398.1 |
RefSeq Size | 2682 |
RefSeq ORF | 1542 |
Locus ID | 1758 |
Protein Families | Secreted Protein |
MW | 55.78 kDa |
Gene Summary | Dentin matrix acidic phosphoprotein is an extracellular matrix protein and a member of the small integrin binding ligand N-linked glycoprotein family. This protein, which is critical for proper mineralization of bone and dentin, is present in diverse cells of bone and tooth tissues. The protein contains a large number of acidic domains, multiple phosphorylation sites, a functional arg-gly-asp cell attachment sequence, and a DNA binding domain. In undifferentiated osteoblasts it is primarily a nuclear protein that regulates the expression of osteoblast-specific genes. During osteoblast maturation the protein becomes phosphorylated and is exported to the extracellular matrix, where it orchestrates mineralized matrix formation. Mutations in the gene are known to cause autosomal recessive hypophosphatemia, a disease that manifests as rickets and osteomalacia. The gene structure is conserved in mammals. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC303479 | DMP1 (untagged)-Human dentin matrix acidic phosphoprotein 1 (DMP1), transcript variant 1 |
USD 760.00 |
|
RC218741 | DMP1 (Myc-DDK-tagged)-Human dentin matrix acidic phosphoprotein 1 (DMP1), transcript variant 1 |
USD 420.00 |
|
RG218741 | DMP1 (GFP-tagged) - Human dentin matrix acidic phosphoprotein 1 (DMP1), transcript variant 1 |
USD 460.00 |
|
RC218741L1 | Lenti ORF clone of Human dentin matrix acidic phosphoprotein 1 (DMP1), transcript variant 1, Myc-DDK-tagged |
USD 768.00 |
|
RC218741L2 | Lenti ORF clone of Human dentin matrix acidic phosphoprotein 1 (DMP1), transcript variant 1, mGFP tagged |
USD 620.00 |
|
RC218741L4 | Lenti ORF clone of Human dentin matrix acidic phosphoprotein 1 (DMP1), transcript variant 1, mGFP tagged |
USD 620.00 |
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