TAF1C (NM_005679) Human Tagged ORF Clone

CAT#: RC218836

TAF1C (Myc-DDK-tagged)-Human TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa (TAF1C), transcript variant 1

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: TAF1C
• Synonyms: MGC:39976; SL1; TAFI95; TAFI110
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC218836 representing NM_005679
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGACTTCCCCAGCTCCCTCCGCCCTGCATTGTTTCTGACCGGCCCCCTTGGTCTGAGCGACGTCCCTG
  ACCTCTCTTTCATGTGCAGCTGGCGAGACGCACTGACTCTGCCAGAGGCCCAGCCCCAGAACTCAGAGAA
  TGGGGCACTGCATGTGACCAAGGACCTGCTGTGGGAGCCGGCAACCCCTGGGCCTCTCCCCATGCTGCCT
  CCCCTCATCGATCCCTGGGACCCTGGCCTGACTGCCCGGGACCTGCTTTTCCGCGGAGGGTGCCGGTATC
  GGAAGCGGCCCCGAGTCGTGCTGGATGTGACTGAGCAGATCAGCCGGTTCCTCTTGGATCATGGAGACGT
  AGCCTTTGCGCCCCTGGGGAAGCTGATGCTGGAGAATTTCAAGCTGGAGGGAGCGGGGAGCCGCACTAAG
  AAGAAGACAGTGGTCAGTGTGAAGAAGCTGCTCCAGGACCTCGGTGGACACCAGCCCTGGGGGTGTCCCT
  GGGCTTACCTCAGCAACCGACAGCGCCGCTTCTCTATCCTCGGGGGCCCCATCCTGGGCACGTCGGTGGC
  GAGCCACTTGGCAGAGCTGCTGCACGAGGAGCTGGTGCTGCGGTGGGAGCAGCTGCTTCTGGATGAGGCC
  TGCACTGGGGGCGCGCTGGCCTGGGTTCCTGGAAGGACACCCCAGTTCGGGCAGCTGGTCTACCCTGCTG
  GAGGCGCCCAGGACAGGCTGCATTTCCAAGAGGTCGTTCTGACCCCAGGTGACAATCCCCAATTCCTTGG
  GAAACCTGGACGCATCCAGCTCCAGGGACCTGTCCGGCAAGTGGTGACATGCACCGTCCAGGGAGAAAGT
  AAGGCCCTTATATACACTTTCCTCCCTCACTGGCTGACCTGCTACCTGACCCCTGGCCCTTTCCATCCCT
  CCTCAGCTCTGCTGGCCGTCCGCTCTGACTACCACTGTGCCGTGTGGAAGTTTGGTAAACAGTGGCAGCC
  AACCCTTCTGCAGGCAATGCAGGTGGAGAAAGGGGCCACGGGGATCAGCCTCAGCCCTCACCTGCCCGGG
  GAGCTGGCCATCTGCAGCCGCTCGGGAGCCGTCTGCCTGTGGAGCCCTGAGGATGGGCTGCGGCAAATCT
  ACAGGGACCCTGAGACCCTCGTGTTCCGGGACTCCTCTTCGTGGCGTTGGGCAGACTTCACTGCGCACCC
  TCGGGTGCTGACCGTGGGTGACCGCACCGGAGTGAAGATGCTGGACACTCAGGGCCCGCCGGGCTGTGGT
  CTGTTGCTTTTTCGTTTGGGGGCAGAGGCTTCGTGCCAGAAAGGGGAACGTGTCCTGCTTACCCAGTACC
  TGGGGCACTCCAGCCCCAAATGCCTCCCCCCTACTCTTCATCTCGTCTGTACCCAGTTCTCTCTCTACCT
  AGTGGACGAGCGCCTTCCCCTGGTGCCGATGCTGAAGTGGAACCATGGCCTCCCCTCCCCGCTCCTGCTG
  GCCCGACTGCTGCCTCCGCCCCGGCCCAGCTGCGTGCAGCCCCTGCTCCTCGGAGGCCAGGGTGGGCAGC
  TGCAGCTGCTGCACCTGGCAGGAGAAGGGGCGTCGGTGCCCCGCCTGGCAGGCCCCCCCCAGTCTCTTCC
  TTCCAGGATCGACTCCCTCCCTGCATTTCCTCTGCTGGAGCCTAAGATCCAGTGGCGGCTGCAGGAGCGC
  CTGAAAGCACCGACCATAGGTCTGGCTGCCGTCGTCCCGCCCTTGCCCTCAGCGCCCACACCAGGCCTGG
  TGCTCTTCCAGCTCTCGGCGGCGGGAGATGTCTTCTACCAGCAGCTCCGCCCCCAGGTGGACTCCAGCCT
  CCGCAGAGATGCTGGGCCTCCTGGCGACACCCAACCTGACTGCCATGCCCCCACAGCTTCCTGGACCTCC
  CAGGACACTGCCGGCTGCAGCCAGTGGCTGAAGGCCCTGCTAAAAGTGCCCCTGGCTCCTCCTGTGTGGA
  CAGCACCCACCTTCACCCACCGCCAGATGCTGGGCAGCACAGAGCTGCGGAGGGAGGAAGAGGAAGGGCA
  GCGGCTGGGTGTGCTCCGCAAGGCCATGGCCCGAGGGCAGCTCCTGCTGCAGAGAGACCTGGGCTCCCTC
  CCTGCGGCAGAGCCACCCCCTGCACCCGAGTCAGGCCTAGAGGACAAGCTCAGTGAGCGCCTGGGGGAAG
  CCTGGGCAGGCCGAGGGGCTGCCTGGTGGGAGAGGCAGCAGGGCAGGACCTCGGAGCCCGGGAGACAGAC
  CAGGCGGCCCAAGCGCCGGACCCAGCTGTCCAGCAGCTTTTCGCTCAGTGGCCATGTGGATCCCTCAGAG
  GACACCAGCTCCCCTCATAGCCCTGAGTGGCCACCTGCTGATGCTCTGCCCCTGCCCCCCACGACCCCGC
  CCTCCCAGGAGTTGACTCCGGATGCATGCGCCCAGGGCGTCCCATCAGAGCAGCGGCAGATGCTCCGTGA
  CTACATGGCCAAGCTACCACCCCAGAGGGACACCCCAGGCTGTGCCACCACACCTCCCCACTCCCAGGCC
  TCCAGCGTCCGGGCCACTCGCTCCCAGCAGCACACACCCGTCCTCTCTAGCTCTCAGCCCCTCCGGAAGA
  AGCCTCGAATGGGCTTC
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC218836 representing NM_005679
  Red=Cloning site Green=Tags(s)
  
  MDFPSSLRPALFLTGPLGLSDVPDLSFMCSWRDALTLPEAQPQNSENGALHVTKDLLWEPATPGPLPMLP
  PLIDPWDPGLTARDLLFRGGCRYRKRPRVVLDVTEQISRFLLDHGDVAFAPLGKLMLENFKLEGAGSRTK
  KKTVVSVKKLLQDLGGHQPWGCPWAYLSNRQRRFSILGGPILGTSVASHLAELLHEELVLRWEQLLLDEA
  CTGGALAWVPGRTPQFGQLVYPAGGAQDRLHFQEVVLTPGDNPQFLGKPGRIQLQGPVRQVVTCTVQGES
  KALIYTFLPHWLTCYLTPGPFHPSSALLAVRSDYHCAVWKFGKQWQPTLLQAMQVEKGATGISLSPHLPG
  ELAICSRSGAVCLWSPEDGLRQIYRDPETLVFRDSSSWRWADFTAHPRVLTVGDRTGVKMLDTQGPPGCG
  LLLFRLGAEASCQKGERVLLTQYLGHSSPKCLPPTLHLVCTQFSLYLVDERLPLVPMLKWNHGLPSPLLL
  ARLLPPPRPSCVQPLLLGGQGGQLQLLHLAGEGASVPRLAGPPQSLPSRIDSLPAFPLLEPKIQWRLQER
  LKAPTIGLAAVVPPLPSAPTPGLVLFQLSAAGDVFYQQLRPQVDSSLRRDAGPPGDTQPDCHAPTASWTS
  QDTAGCSQWLKALLKVPLAPPVWTAPTFTHRQMLGSTELRREEEEGQRLGVLRKAMARGQLLLQRDLGSL
  PAAEPPPAPESGLEDKLSERLGEAWAGRGAAWWERQQGRTSEPGRQTRRPKRRTQLSSSFSLSGHVDPSE
  DTSSPHSPEWPPADALPLPPTTPPSQELTPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQA
  SSVRATRSQQHTPVLSSSQPLRKKPRMGF
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_005679
• ORF Size: 2607 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_005679.1, NM_005679.2, NM_005679.3, NP_005670.2, NP_005670.3
• RefSeq Size: 3925
• RefSeq ORF: 2610
• Locus ID: 9013
• Protein Families: Transcription Factors
• MW: 95 kDa
• Gene Summary: Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the largest SL1-specific TAF. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2011]