CEBP Alpha (CEBPA) (NM_004364) Human Tagged ORF Clone
CAT#: RC218955L3
- LentiORF®
Lenti ORF clone of Human CCAAT/enhancer binding protein (C/EBP), alpha (CEBPA), Myc-DDK-tagged
"NM_004364" in other vectors (6)
Product Images
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | CEBPA |
Synonyms | C/EBP-alpha; CEBP |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC218955).
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Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_004364 |
ORF Size | 1074 bp |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_004364.2, NP_004355.2 |
RefSeq Size | 2385 |
RefSeq ORF | 1077 |
Locus ID | 1050 |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS |
Protein Pathways | Acute myeloid leukemia, Pathways in cancer |
MW | 37.4 kDa |
Gene Summary | This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of this gene is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons. [provided by RefSeq, Dec 2013] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC303472 | CEBPA (untagged)-Human CCAAT/enhancer binding protein (C/EBP), alpha (CEBPA) |
USD 610.00 |
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RC218955 | CEBPA (Myc-DDK-tagged)-Human CCAAT/enhancer binding protein (C/EBP), alpha (CEBPA) |
USD 420.00 |
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RG218955 | CEBPA (GFP-tagged) - Human CCAAT/enhancer binding protein (C/EBP), alpha (CEBPA) |
USD 460.00 |
|
RC218955L1 | Lenti ORF clone of Human CCAAT/enhancer binding protein (C/EBP), alpha (CEBPA), Myc-DDK-tagged |
USD 768.00 |
|
RC218955L2 | Lenti ORF clone of Human CCAAT/enhancer binding protein (C/EBP), alpha (CEBPA), mGFP tagged |
USD 768.00 |
|
RC218955L4 | Lenti ORF clone of Human CCAAT/enhancer binding protein (C/EBP), alpha (CEBPA), mGFP tagged |
USD 620.00 |
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