HS6ST2 (NM_001077188) Human Tagged ORF Clone

CAT#: RC220043

HS6ST2 (Myc-DDK-tagged)-Human heparan sulfate 6-O-sulfotransferase 2 (HS6ST2), transcript variant L

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: HS6ST2
• Synonyms: MRXSPM
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC220043 representing NM_001077188
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCACTGCCTGCGTGTGCAGTCCGGGAGTTCGAGCCGCCGCGGCAACCGGAGCGAGGAGCGCCCGTCC
  GCACCACCTGTCCCCGCCGGCATTCCAGAGTAGAGGCCGAATTGGCAGCGAGCCGGCCCGGGTCGGTCGC
  CGCCTCAGTTCGCGCGGGCCCTCCTAGGGGTGTGTCTCACGGATTCCACACCCGGCCGCTCCTGGACAAG
  CCCCGAAAGGCGTCTTCTTCCCTGGCGGGAGCCGCGTGCGCCCCGCTTTTCGCGCTGCTGTCCCGGGGCC
  GCCGCAGGCGGATGCACGTCCTCAGGCGACGCTGGGACCTGGGCTCCCTCTGCCGGGCCCTGCTCACTCG
  GGGCCTGGCCGCCCTGGGCCACTCGCTGAAGCACGTGCTCGGTGCGATCTTCTCCAAGATTTTCGGCCCC
  ATGGCCAGCGTCGGGAACATGGATGAGAAATCCAACAAGCTGCTGCTAGCTTTGGTGATGCTCTTCCTAT
  TTGCCGTGATCGTCCTCCAATACGTGTGCCCCGGCACAGAATGCCAGCTCCTCCGCCTGCAGGCGTTCAG
  CTCCCCGGTGCCGGACCCGTACCGCTCGGAGGATGAGAGCTCCGCCAGGTTCGTGCCCCGCTACAATTTC
  ACCCGCGGCGACCTCCTGCGCAAGGTAGACTTCGACATCAAGGGCGATGACCTGATCGTGTTCCTGCACA
  TCCAGAAGACCGGGGGCACCACTTTCGGCCGCCACTTGGTGCGTAACATCCAGCTGGAGCAGCCGTGCGA
  GTGCCGCGTGGGTCAGAAGAAATGCACTTGCCACCGGCCGGGTAAGCGGGAAACCTGGCTCTTCTCCAGG
  TTCTCCACGGGCTGGAGCTGCGGGTTGCACGCCGACTGGACCGAGCTCACCAGCTGTGTGCCCTCCGTGG
  TGGACGGCAAGCGCGACGCCAGGCTGAGACCGTCCAGGTGGAGGATTTTTCAGATTCTAGATGCAGCAAG
  TAAGGATAAACGGGGTTCTCCAAACACTAACGCAGGCGCCAACTCTCCGTCATCCACAAAGACCCGGAAC
  ACATCTAAGAGTGGGAAGAACTTCCACTACATCACCATCCTCCGAGACCCAGTGTCCCGGTACTTGAGTG
  AGTGGAGGCATGTCCAGAGAGGGGCAACATGGAAAGCATCCCTGCATGTCTGCGATGGAAGGCCTCCAAC
  CTCCGAAGAGCTGCCCAGCTGCTACACTGGCGATGACTGGTCTGGCTGCCCCCTCAAAGAGTTTATGGAC
  TGTCCCTACAATCTAGCCAACAACCGCCAGGTGCGCATGCTCTCCGACCTGACCCTGGTAGGCTGCTACA
  ACCTCTCTGTCATGCCTGAAAAGCAAAGAAACAAGGTCCTTCTGGAAAGTGCCAAGTCAAATCTGAAGCA
  CATGGCGTTCTTCGGCCTCACTGAGTTTCAGCGGAAGACCCAATATCTGTTTGAGAAAACCTTCAACATG
  AACTTTATTTCGCCATTTACCCAGTATAATACCACTAGGGCCTCTAGTGTAGAGATCAATGAGGAAATTC
  AAAAGCGTATTGAGGGACTGAATTTTCTGGATATGGAGTTGTACAGCTATGCCAAAGACCTTTTTTTGCA
  GAGGTATCAGTTTATGAGGCAGAAAGAGCATCAGGAGGCCAGGCGAAAGCGTCAGGAACAACGCAAATTT
  CTGAAGGGAAGGCTCCTTCAGACCCATTTCCAGAGCCAGGGTCAGGGCCAGAGCCAGAATCCGAATCAGA
  ATCAGAGTCAGAACCCAAATCCGAATGCCAATCAGAACCTGACTCAGAATCTGATGCAGAATCTGACTCA
  GAGTTTGAGCCAGAAGGAGAACCGGGAAAGCCCGAAGCAGAACTCAGGCAAGGAGCAGAATGATAACACC
  AGCAATGGCACCAACGACTACATAGGCAGTGTAGAGAAATGGCGT
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC220043 representing NM_001077188
  Red=Cloning site Green=Tags(s)
  
  MALPACAVREFEPPRQPERGAPVRTTCPRRHSRVEAELAASRPGSVAASVRAGPPRGVSHGFHTRPLLDK
  PRKASSSLAGAACAPLFALLSRGRRRRMHVLRRRWDLGSLCRALLTRGLAALGHSLKHVLGAIFSKIFGP
  MASVGNMDEKSNKLLLALVMLFLFAVIVLQYVCPGTECQLLRLQAFSSPVPDPYRSEDESSARFVPRYNF
  TRGDLLRKVDFDIKGDDLIVFLHIQKTGGTTFGRHLVRNIQLEQPCECRVGQKKCTCHRPGKRETWLFSR
  FSTGWSCGLHADWTELTSCVPSVVDGKRDARLRPSRWRIFQILDAASKDKRGSPNTNAGANSPSSTKTRN
  TSKSGKNFHYITILRDPVSRYLSEWRHVQRGATWKASLHVCDGRPPTSEELPSCYTGDDWSGCPLKEFMD
  CPYNLANNRQVRMLSDLTLVGCYNLSVMPEKQRNKVLLESAKSNLKHMAFFGLTEFQRKTQYLFEKTFNM
  NFISPFTQYNTTRASSVEINEEIQKRIEGLNFLDMELYSYAKDLFLQRYQFMRQKEHQEARRKRQEQRKF
  LKGRLLQTHFQSQGQGQSQNPNQNQSQNPNPNANQNLTQNLMQNLTQSLSQKENRESPKQNSGKEQNDNT
  SNGTNDYIGSVEKWR
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001077188
• ORF Size: 1935 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001077188.1, NP_001070656.1
• RefSeq Size: 4576
• RefSeq ORF: 1938
• Locus ID: 90161
• Protein Families: Transmembrane
• Protein Pathways: Heparan sulfate biosynthesis
• MW: 73.2 kDa
• Gene Summary: Heparan sulfate proteoglycans are ubiquitous components of the cell surface, extracellular matrix, and basement membranes, and interact with various ligands to influence cell growth, differentiation, adhesion, and migration. This gene encodes a member of the heparan sulfate (HS) sulfotransferase gene family, which catalyze the transfer of sulfate to HS. Different family members and isoforms are thought to synthesize heparan sulfates with tissue-specific structures and functions. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]