BACE1 (NM_138971) Human Tagged ORF Clone
CAT#: RC220224L3
- LentiORF®
Lenti ORF clone of Human beta-site APP-cleaving enzyme 1 (BACE1), transcript variant c, Myc-DDK-tagged
"NM_138971" in other vectors (4)
Product Images
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | BACE1 |
Synonyms | ASP2; BACE; HSPC104 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC220224).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_138971 |
ORF Size | 1371 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_138971.2, NP_620427.1 |
RefSeq Size | 5718 |
RefSeq ORF | 1374 |
Locus ID | 23621 |
Protein Families | Druggable Genome, Protease, Transmembrane |
Protein Pathways | Alzheimer's disease |
MW | 46.3 kDa |
Gene Summary | This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques, which accumulate in the brains of human Alzheimer's disease patients. [provided by RefSeq, Nov 2015] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC313560 | BACE1 (untagged)-Human beta-site APP-cleaving enzyme 1 (BACE1), transcript variant c |
USD 770.00 |
|
RC220224 | BACE1 (Myc-DDK-tagged)-Human beta-site APP-cleaving enzyme 1 (BACE1), transcript variant c |
USD 430.00 |
|
RG220224 | BACE1 (GFP-tagged) - Human beta-site APP-cleaving enzyme 1 (BACE1), transcript variant c |
USD 470.00 |
|
RC220224L4 | Lenti ORF clone of Human beta-site APP-cleaving enzyme 1 (BACE1), transcript variant c, mGFP tagged |
USD 630.00 |
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