Cullin 4B (CUL4B) (NM_001079872) Human Tagged ORF Clone

CAT#: RC220405L3

Lenti-ORF clone of CUL4B (Myc-DDK-tagged)-Human cullin 4B (CUL4B), transcript variant 2

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: CUL4B
• Synonyms: CUL-4B; MRXHF2; MRXS15; MRXSC; SFM2
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC220405).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_001079872
• ORF Size: 2685 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001079872.1, NP_001073341.1
• RefSeq Size: 5198
• RefSeq ORF: 2688
• Locus ID: 8450
• Protein Pathways: Nucleotide excision repair, Ubiquitin mediated proteolysis
• MW: 102.1 kDa
• Gene Summary: This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]