Tyrosinase (TYR) (NM_000372) Human Tagged ORF Clone
CAT#: RC221797L4
- LentiORF®
Lenti ORF clone of Human tyrosinase (oculocutaneous albinism IA) (TYR), mGFP tagged
"NM_000372" in other vectors (6)
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | mGFP |
Symbol | TYR |
Synonyms | ATN; CMM8; OCA1; OCA1A; OCAIA; SHEP3 |
Vector | pLenti-C-mGFP-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC221797).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_000372 |
ORF Size | 1587 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers. |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_000372.3, NP_000363.1 |
RefSeq Size | 1964 bp |
RefSeq ORF | 1590 bp |
Locus ID | 7299 |
UniProt ID | P14679, L8B082 |
Cytogenetics | 11q14.3 |
Protein Families | Transmembrane |
Protein Pathways | Melanogenesis, Metabolic pathways, Riboflavin metabolism, Tyrosine metabolism |
MW | 60.39 kDa |
Gene Summary | 'The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. [provided by RefSeq, Oct 2008]' |
Documents
Product Manuals |
FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC300059 | TYR (untagged)-Human tyrosinase (oculocutaneous albinism IA) (TYR) |
USD 900.00 |
|
RC221797 | TYR (Myc-DDK-tagged)-Human tyrosinase (oculocutaneous albinism IA) (TYR) |
USD 480.00 |
|
RG221797 | TYR (GFP-tagged) - Human tyrosinase (oculocutaneous albinism IA) (TYR) |
USD 530.00 |
|
RC221797L1 | Lenti ORF clone of Human tyrosinase (oculocutaneous albinism IA) (TYR), Myc-DDK-tagged |
USD 840.00 |
|
RC221797L2 | Lenti ORF clone of Human tyrosinase (oculocutaneous albinism IA) (TYR), mGFP tagged |
USD 680.00 |
|
RC221797L3 | Lenti ORF clone of Human tyrosinase (oculocutaneous albinism IA) (TYR), Myc-DDK-tagged |
USD 680.00 |
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