KCNH6 (NM_173092) Human Tagged ORF Clone
CAT#: RC222145
KCNH6 (Myc-DDK-tagged)-Human potassium voltage-gated channel, subfamily H (eag-related), member 6 (KCNH6), transcript variant 2
"NM_173092" in other vectors (4)
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | KCNH6 |
Synonyms | ERG-2; ERG2; hERG-2; HERG2; Kv11.2 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RC222145 representing NM_173092
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCCGGTCCGCAGGGGCCACGTCGCTCCCCAAAACACTTACCTGGACACCATCATCCGCAAGTTCGAGG GCCAAAGTCGGAAGTTCCTGATTGCCAATGCTCAGATGGAGAACTGCGCCATCATTTACTGCAACGACGG CTTCTGCGAACTCTTCGGCTACTCCCGAGTGGAGGTGATGCAGCAACCCTGCACCTGCGACTTCCTCACA GGCCCCAACACACCAAGCAGCGCCGTGTCCCGCCTAGCGCAGGCCCTGCTGGGGGCTGAGGAGTGCAAGG TGGACATCCTCTACTACCGCAAGGATGCCTCCAGCTTCCGCTGCCTGGTAGATGTGGTGCCCGTGAAGAA CGAGGACGGGGCTGTCATCATGTTCATTCTCAACTTCGAGGACCTGGCCCAGCTCCTGGCCAAGTGCAGC AGCCGCAGCTTGTCCCAGCGCCTGTTGTCCCAGAGCTTCCTGGGCTCCGAGGGCTCTCACGGCAGGCCAG GCGGACCAGGGCCAGGCACAGGCAGGGGCAAGTACAGGACCATCAGCCAGATCCCACAGTTCACGCTCAA CTTCGTGGAGTTCAACTTGGAGAAGCACCGCTCCAGCTCCACCACGGAGATTGAGATCATCGCGCCCCAT AAGGTGGTGGAGCGGACACAGAACGTCACTGAGAAGGTCACCCAGGTCCTGTCCCTGGGCGCGGATGTGC TGCCGGAGTACAAGCTGCAGGCGCCGCGCATCCACCGCTGGACCATCCTGCACTACAGCCCCTTCAAGGC CGTGTGGGACTGGCTCATCCTGCTGCTGGTCATCTACACGGCTGTCTTCACGCCCTACTCAGCCGCCTTC CTGCTCAGCGACCAGGACGAATCACGGCGTGGGGCCTGCAGCTATACCTGCAGTCCCCTCACTGTGGTGG ATCTCATCGTGGACATCATGTTCGTCGTGGACATCGTCATCAACTTCCGCACCACCTATGTCAACACCAA TGATGAGGTGGTCAGCCACCCCCGCCGCATCGCCGTCCACTACTTCAAGGGCTGGTTCCTCATTGACATG GTGGCCGCCATCCCTTTCGACCTCCTGATCTTCCGCACTGGCTCCGATGAGACCACAACCCTGATTGGGC TATTGAAGACAGCGCGGCTGCTGCGGCTGGTGCGCGTAGCACGGAAGCTGGACCGCTACTCTGAGTATGG GGCGGCTGTGCTCTTCTTGCTCATGTGCACCTTCGCGCTCATAGCGCACTGGCTGGCCTGCATCTGCAGC CTCACCAGCGTGGGCTTCGGCAATGTCTCGCCCAACACCAACTCCGAGAAGGTCTTCTCCATCTGCGTCA TGCTCATCGGCTCCCTGATGTACGCCAGCATCTTCGGGAACGTGTCCGCGATCATCCAGCGCCTGTACTC GGGCACCGCGCGCTACCACACGCAGATGCTGCGTGTCAAGGAGTTCATCCGCTTCCACCAGATCCCCAAC CCACTGCGCCAGCGCCTGGAGGAGTATTTCCAGCACGCCTGGTCCTACACCAATGGCATTGACATGAACG CGGTGCTGAAGGGCTTCCCCGAGTGCCTGCAGGCTGACATCTGCCTGCACCTGCACCGCGCACTGCTGCA GCACTGCCCAGCTTTCAGCGGCGCCGGCAAGGGCTGCCTGCGCGCGCTAGCCGTCAAGTTCAAGACCACC CACGCGCCGCCTGGGGACACGCTGGTGCACCTCGGCGACGTGCTCTCCACCCTCTACTTCATCTCCCGAG GCTCCATCGAGATCCTGCGCGACGACGTGGTCGTGGCCATCCTAGGAAAGAATGACATCTTTGGGGAACC CGTCAGCCTCCATGCCCAGCCAGGCAAGTCCAGTGCAGACGTGCGGGCTCTGACCTACTGCGACCTGCAC AAGATCCAGCGGGCAGATCTGCTGGAGGTGCTGGACATGTACCCGGCCTTTGCGGAGAGCTTCTGGAGTA AGCTGGAGGTCACCTTCAACCTGCGGGACGCAGCCGGGGGTCTCCACTCATCCCCCCGACAGGCTCCTGG CAGCCAAGACCACCAAGGTTTCTTTCTCAGTGACAACCAGTCAGATGCAGCCCCTCCCCTGAGCATCTCA GATGCATCTGGCCTCTGGCCTGAGCTACTGCAGGAAATGCCCCCAAGGCACAGCCCCCAAAGCCCTCAGG AAGACCCAGATTGCTGGCCTCTGAAGCTGGGCTCCAGGCTAGAGCAGCTCCAGGCCCAGATGAACAGGCT GGAGTCCCGCGTGTCCTCAGACCTCAGCCGCATCTTGCAGCTCCTCCAGAAGCCCATGCCCCAGGGCCAC GCCAGCTACATTCTGGAAGCCCCTGCCTCCAATGACCTGGCCTTGGTTCCTATAGCCTCGGAGACGACGA GTCCAGGGCCCAGGCTGCCCCAGGGCTTTCTGCCTCCTGCACAGACCCCAAGCTATGGAGACTTGGATGA CTGTAGTCCAAAGCACAGGAACTCCTCCCCCAGGATGCCTCACCTGGCTGTGGCAACGGACAAAACTCTG GCACCATCCTCAGAACAGGAACAGCCTGAGGGGCTCTGGCCACCCCTAGCCTCACCTCTACATCCCCTGG AAGTACAAGGACTCATCTGTGGTCCCTGCTTCTCCTCCCTCCCTGAACACCTTGGCTCTGTTCCCAAGCA GCTGGACTTCCAGAGACATGGCTCAGATCCTGGATTTGCAGGGAGTTGGGGCCAC ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC222145 representing NM_173092
Red=Cloning site Green=Tags(s) MPVRRGHVAPQNTYLDTIIRKFEGQSRKFLIANAQMENCAIIYCNDGFCELFGYSRVEVMQQPCTCDFLT GPNTPSSAVSRLAQALLGAEECKVDILYYRKDASSFRCLVDVVPVKNEDGAVIMFILNFEDLAQLLAKCS SRSLSQRLLSQSFLGSEGSHGRPGGPGPGTGRGKYRTISQIPQFTLNFVEFNLEKHRSSSTTEIEIIAPH KVVERTQNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAF LLSDQDESRRGACSYTCSPLTVVDLIVDIMFVVDIVINFRTTYVNTNDEVVSHPRRIAVHYFKGWFLIDM VAAIPFDLLIFRTGSDETTTLIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACICS LTSVGFGNVSPNTNSEKVFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVKEFIRFHQIPN PLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLHRALLQHCPAFSGAGKGCLRALAVKFKTT HAPPGDTLVHLGDVLSTLYFISRGSIEILRDDVVVAILGKNDIFGEPVSLHAQPGKSSADVRALTYCDLH KIQRADLLEVLDMYPAFAESFWSKLEVTFNLRDAAGGLHSSPRQAPGSQDHQGFFLSDNQSDAAPPLSIS DASGLWPELLQEMPPRHSPQSPQEDPDCWPLKLGSRLEQLQAQMNRLESRVSSDLSRILQLLQKPMPQGH ASYILEAPASNDLALVPIASETTSPGPRLPQGFLPPAQTPSYGDLDDCSPKHRNSSPRMPHLAVATDKTL APSSEQEQPEGLWPPLASPLHPLEVQGLICGPCFSSLPEHLGSVPKQLDFQRHGSDPGFAGSWGH TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Chromatograms |
CHROMATOGRAMS
![]() Sequencher program is needed, download here. |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_173092 |
ORF Size | 2715 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers. |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_173092.1, NM_173092.2, NP_775115.1 |
RefSeq Size | 3017 bp |
RefSeq ORF | 2718 bp |
Locus ID | 81033 |
Protein Families | Druggable Genome, Ion Channels: Other, Transmembrane |
MW | 100.3 kDa |
Gene Summary | Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013] |
Documents
Product Manuals |
FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC306789 | KCNH6 (untagged)-Human potassium voltage-gated channel, subfamily H (eag-related), member 6 (KCNH6), transcript variant 2 |
USD 1,830.00 |
|
RG222145 | KCNH6 (GFP-tagged) - Human potassium voltage-gated channel, subfamily H (eag-related), member 6 (KCNH6), transcript variant 2 |
USD 830.00 |
|
RC222145L3 | Lenti ORF clone of Human potassium voltage-gated channel, subfamily H (eag-related), member 6 (KCNH6), transcript variant 2, Myc-DDK-tagged |
USD 950.00 |
|
RC222145L4 | Lenti ORF clone of Human potassium voltage-gated channel, subfamily H (eag-related), member 6 (KCNH6), transcript variant 2, mGFP tagged |
USD 950.00 |
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