TIAM2 (NM_012454) Human Tagged ORF Clone
CAT#: RC222386
- TrueORF®
TIAM2 (Myc-DDK-tagged)-Human T-cell lymphoma invasion and metastasis 2 (TIAM2), transcript variant 1
"NM_012454" in other vectors (2)
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Other products for "TIAM2"
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | TIAM2 |
Synonyms | STEF; TIAM-2 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RC222386 representing NM_012454
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGGCAACTCCGACAGTCAGTACACCCTTCAAGGATCTAAAAATCATAGCAATACTATTACTGGTGCTA AGCAAATTCCTTGCTCCCTGAAAATACGTGGCATTCATGCAAAAGAGGAAAAGTCATTGCATGGATGGGG TCACGGAAGCAACGGAGCAGGTTACAAGTCCAGGTCCCTGGCCCGAAGCTGCCTTTCTCACTTTAAGAGT AACCAGCCTTACGCATCGAGACTCGGTGGCCCCACATGCAAGGTCTCCAGAGGTGTTGCCTACTCCACGC ACAGGACAAATGCCCCAGGGAAGGATTTCCAGGGCATCAGTGCTGCTTTCTCAACTGAGAATGGCTTCCA CTCTGTTGGCCACGAGCTGGCAGATAACCACATCACCTCCAGAGACTGCAACGGACACCTTCTCAACTGC TACGGGAGGAATGAGAGCATTGCCTCCACCCCACCGGGCGAAGACCGCAAGAGCCCCCGAGTGCTCATCA AAACGCTGGGGAAGCTGGATGGGTGTTTAAGGGTCGAGTTCCACAATGGTGGCAACCCCAGCAAAGTGCC TGCAGAGGACTGCAGTGAGCCGGTGCAGCTGCTGAGGTACTCACCTACCTTAGCATCGGAAACCTCCCCT GTGCCTGAAGCCAGGAGGGGGTCCAGCGCCGATTCCCTGCCCAGCCATCGCCCCTCTCCCACGGACTCTC GCCTGCGGTCCAGCAAAGGCAGCTCCCTGAGTTCTGAGTCATCCTGGTACGACTCCCCTTGGGGCAATGC TGGAGAGCTGAGCGAGGCTGAGGGCTCCTTCCTGGCCCCCGGCATGCCTGACCCCAGTCTCCATGCCAGC TTCCCACCTGGCGATGCCAAAAAGCCTTTCAACCAAAGCTCTTCCCTCTCCTCCCTCCGGGAACTGTACA AAGATGCCAACCTGGGGAGCCTCTCCCCCTCAGGTATCCGCCTTTCTGATGAATACATGGGCACGCATGC CAGCCTGAGCAACCGTGTCTCTTTTGCTTCCGACATTGATGTGCCCTCCAGAGTGGCACACGGGGACCCC ATCCAGTACAGTTCCTTCACTCTCCCCTGTCGGAAGCCCAAAGCCTTTGTTGAGGATACTGCGAAGAAGG ACTCCCTCAAAGCCAGGATGCGACGGATCAGTGACTGGACGGGAAGCCTCTCAAGGAAGAAAAGGAAACT CCAGGAGCCGAGGTCCAAGGAGGGCAGTGACTACTTTGACAGTCGCTCTGATGGACTGAATACAGATGTG CAGGGATCCTCCCAGGCATCTGCTTTTCTGTGGTCAGGGGGCTCTACTCAGATCCTGTCTCAGAGAAGTG AATCCACACATGCGATTGGCAGCGATCCCCTCCGGCAGAACATTTATGAGAATTTCATGCGAGAGTTGGA AATGAGCAGGACCAACACTGAGAACATAGAAACATCTACAGAAACCGCCGAGTCCAGCAGCGAGTCACTC AGCTCTCTGGAACAGCTGGATCTGCTCTTTGAGAAGGAACAGGGGGTGGTCCGGAAGGCCGGGTGGCTCT TCTTCAAGCCCCTGGTCACTGTGCAGAAGGAAAGGAAGCTTGAGCTGGTGGCACGAAGGAAATGGAAACA GTACTGGGTAACGCTGAAAGGATGCACGCTGCTGTTTTATGAGACCTATGGGAAGAATTCCATGGATCAG AGCAGTGCCCCTCGGTGTGCTCTGTTTGCAGAAGACAGCATAGTGCAGTCTGTTCCAGAGCATCCCAAGA AAGAAAATGTGTTCTGCCTCAGCAACTCCTTTGGAGATGTCTACCTTTTCCAGGCCACCAGCCAGACAGA TCTAGAAAACTGGGTCACTGCTGTACACTCTGCTTGTGCATCCCTTTTTGCAAAGAAGCATGGGAAAGAG GACACGCTGCGGCTGCTGAAGAACCAGACCAAAAACCTGCTTCAGAAGATAGACATGGACAGCAAGATGA AGAAGATGGCAGAGCTGCAGCTGTCCGTGGTGAGCGACCCAAAGAACAGGAAAGCCATAGAGAACCAGAT CCAGCAATGGGAGCAGAATCTTGAGAAATTTCACATGGATCTGTTCAGGATGCGCTGCTATCTGGCCAGC CTACAAGGTGGGGAGTTACCGAACCCAAAGAGTCTCCTTGCAGCCGCCAGCCGCCCCTCCAAGCTGGCCC TCGGCAGGCTGGGCATCTTGTCTGTTTCCTCTTTCCATGCTCTGGTATGTTCTAGAGATGACTCTGCTCT CCGGAAAAGGACACTGTCACTGACCCAGCGAGGGAGAAACAAGAAGGGAATATTTTCTTCGTTAAAAGGG CTGGACACACTGGCCAGAAAAGGCAAGGAGAAGAGACCTTCTATAACTCAGGTCGATGAACTTCTGCATA TATATGGTTCAACAGTAGACGGTGTTCCCCGAGACAATGCATGGGAAATCCAGACTTATGTCCACTTTCA GGACAATCACGGAGTTACTGTAGGGATCAAGCCAGAGCACAGAGTAGAAGATATTTTGACTTTGGCATGC AAGATGAGGCAGTTGGAACCCAGCCATTATGGCCTACAGCTTCGAAAATTAGTAGATGACAATGTTGAGT ATTGCATCCCTGCACCATATGAATATATGCAACAACAGGTTTATGATGAAATAGAAGTCTTTCCACTAAA TGTTTATGACGTGCAGCTCACGAAGACTGGGAGTGTGTGTGACTTTGGGTTTGCAGTTACAGCGCAGGTG GATGAGCGTCAGCATCTCAGCCGGATATTTATAAGCGACGTTCTTCCCGATGGCCTGGCGTATGGGGAAG GGCTGAGAAAGGGCAATGAGATCATGACCTTAAATGGGGAAGCTGTGTCTGATCTTGACCTTAAGCAGAT GGAGGCCCTGTTTTCTGAGAAGAGCGTCGGACTCACTCTGATTGCCCGGCCTCCGGACACAAAAGCAACC CTGTGTACATCCTGGTCAGACAGTGACCTGTTCTCCAGGGACCAGAAGAGTCTGCTGCCCCCTCCTAACC AGTCCCAACTGCTGGAGGAATTCCTGGATAACTTTAAAAAGAATACAGCCAATGATTTCAGCAACGTCCC TGATATCACAACAGGTCTGAAAAGGAGTCAGACAGATGGCACTCTGGATCAGGTTTCCCACAGGGAGAAA ATGGAGCAGACATTCAGGAGTGCTGAGCAGATCACTGCACTGTGCAGGAGTTTTAACGACAGTCAGGCCA ACGGCATGGAAGGACCGCGGGAGAATCAGGATCCTCCTCCGAGGCCTCTGGCCCGCCACCTGTCTGATGC AGACCGCCTCCGCAAAGTCATCCAGGAGCTTGTGGACACAGAGAAGTCCTACGTGAAGGATTTGAGCTGC CTCTTTGAATTATACTTGGAGCCACTTCAGAATGAGACCTTTCTTACCCAAGATGAGATGGAGTCACTTT TTGGAAGTTTGCCAGAGATGCTTGAGTTTCAGAAGGTGTTTCTGGAGACCCTGGAGGATGGGATTTCAGC ATCATCTGACTTTAACACCCTAGAAACCCCCTCACAGTTTAGAAAATTACTGTTTTCCCTTGGAGGCTCT TTCCTTTATTACGCGGACCACTTTAAACTGTACAGTGGATTCTGTGCTAACCATATCAAAGTACAGAAGG TTCTGGAGCGAGCTAAAACTGACAAAGCCTTCAAGGCTTTTCTGGACGCCCGGAACCCCACCAAGCAGCA TTCCTCCACGCTGGAGTCCTACCTCATCAAGCCGGTTCAGAGAGTGCTCAAGTACCCGCTGCTGCTCAAG GAGCTGGTGTCCCTGACGGACCAGGAGAGCGAGGAGCACTACCACCTGACGGAAGCACTAAAGGCAATGG AGAAAGTAGCGAGCCACATCAATGAGATGCAGAAGATCTATGAGGATTATGGGACCGTGTTTGACCAGCT AGTAGCTGAGCAGAGCGGAACAGAGAAGGAGGTAACAGAACTTTCGATGGGAGAGCTTCTGATGCACTCT ACGGTTTCCTGGTTGAATCCATTTCTGTCTCTAGGAAAAGCTAGAAAGGACCTTGAGCTCACAGTATTTG TTTTTAAGAGAGCCGTCATACTGGTTTATAAAGAAAACTGCAAACTGAAAAAGAAATTGCCCTCGAATTC CCGGCCTGCACACAACTCTACTGACTTGGACCCATTTAAATTCCGCTGGTTGATCCCCATCTCCGCGCTT CAAGTCAGACTGGGGAATCCAGCAGGGACAGAAAATAATTCCATATGGGAACTGATCCATACGAAGTCAG AAATAGAAGGACGGCCAGAAACCATCTTTCAGTTGTGTTGCAGTGACAGTGAAAGCAAAACCAACATTGT TAAGGTGATTCGTTCTATTCTGAGGGAGAACTTCAGGCGTCACATAAAGTGTGAATTACCACTGGAGAAA ACGTGTAAGGATCGCCTGGTACCTCTTAAGAACCGAGTTCCTGTTTCGGCCAAATTAGCTTCATCCAGGT CTTTAAAAGTCCTGAAGAATTCCTCCAGCAACGAGTGGACCGGTGAGACTGGCAAGGGAACCTTGCTGGA CTCTGACGAGGGCAGCTTGAGCAGCGGCACCCAGAGCAGCGGCTGCCCCACGGCTGAGGGCAGGCAGGAC TCCAAGAGCACTTCTCCCGGGAAATACCCACACCCCGGCTTGGCAGATTTTGCCGACAATCTCATCAAAG AGAGTGACATCCTGAGCGATGAAGATGATGACCACCGTCAGACTGTGAAGCAGGGCAGCCCTACTAAAGA CATCGAAATTCAGTTCCAGAGACTGAGGATTTCCGAGGACCCAGACGTTCACCCCGAGGCTGAGCAGCAG CCTGGCCCGGAGTCGGGTGAGGGTCAGAAAGGAGGAGAGCAGCCCAAACTGGTCCGGGGGCACTTCTGCC CCATTAAACGAAAAGCCAACAGCACCAAGAGGGACAGAGGAACTTTGCTCAAGGCGCAGATCCGTCACCA GTCCCTTGACAGTCAGTCTGAAAATGCCACCATCGACCTAAATTCTGTTCTAGAGCGAGAATTCAGTGTC CAGAGTTTAACATCTGTTGTCAGTGAGGAGTGTTTTTATGAAACAGAGAGCCACGGAAAATCA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC222386 representing NM_012454
Red=Cloning site Green=Tags(s) MGNSDSQYTLQGSKNHSNTITGAKQIPCSLKIRGIHAKEEKSLHGWGHGSNGAGYKSRSLARSCLSHFKS NQPYASRLGGPTCKVSRGVAYSTHRTNAPGKDFQGISAAFSTENGFHSVGHELADNHITSRDCNGHLLNC YGRNESIASTPPGEDRKSPRVLIKTLGKLDGCLRVEFHNGGNPSKVPAEDCSEPVQLLRYSPTLASETSP VPEARRGSSADSLPSHRPSPTDSRLRSSKGSSLSSESSWYDSPWGNAGELSEAEGSFLAPGMPDPSLHAS FPPGDAKKPFNQSSSLSSLRELYKDANLGSLSPSGIRLSDEYMGTHASLSNRVSFASDIDVPSRVAHGDP IQYSSFTLPCRKPKAFVEDTAKKDSLKARMRRISDWTGSLSRKKRKLQEPRSKEGSDYFDSRSDGLNTDV QGSSQASAFLWSGGSTQILSQRSESTHAIGSDPLRQNIYENFMRELEMSRTNTENIETSTETAESSSESL SSLEQLDLLFEKEQGVVRKAGWLFFKPLVTVQKERKLELVARRKWKQYWVTLKGCTLLFYETYGKNSMDQ SSAPRCALFAEDSIVQSVPEHPKKENVFCLSNSFGDVYLFQATSQTDLENWVTAVHSACASLFAKKHGKE DTLRLLKNQTKNLLQKIDMDSKMKKMAELQLSVVSDPKNRKAIENQIQQWEQNLEKFHMDLFRMRCYLAS LQGGELPNPKSLLAAASRPSKLALGRLGILSVSSFHALVCSRDDSALRKRTLSLTQRGRNKKGIFSSLKG LDTLARKGKEKRPSITQVDELLHIYGSTVDGVPRDNAWEIQTYVHFQDNHGVTVGIKPEHRVEDILTLAC KMRQLEPSHYGLQLRKLVDDNVEYCIPAPYEYMQQQVYDEIEVFPLNVYDVQLTKTGSVCDFGFAVTAQV DERQHLSRIFISDVLPDGLAYGEGLRKGNEIMTLNGEAVSDLDLKQMEALFSEKSVGLTLIARPPDTKAT LCTSWSDSDLFSRDQKSLLPPPNQSQLLEEFLDNFKKNTANDFSNVPDITTGLKRSQTDGTLDQVSHREK MEQTFRSAEQITALCRSFNDSQANGMEGPRENQDPPPRPLARHLSDADRLRKVIQELVDTEKSYVKDLSC LFELYLEPLQNETFLTQDEMESLFGSLPEMLEFQKVFLETLEDGISASSDFNTLETPSQFRKLLFSLGGS FLYYADHFKLYSGFCANHIKVQKVLERAKTDKAFKAFLDARNPTKQHSSTLESYLIKPVQRVLKYPLLLK ELVSLTDQESEEHYHLTEALKAMEKVASHINEMQKIYEDYGTVFDQLVAEQSGTEKEVTELSMGELLMHS TVSWLNPFLSLGKARKDLELTVFVFKRAVILVYKENCKLKKKLPSNSRPAHNSTDLDPFKFRWLIPISAL QVRLGNPAGTENNSIWELIHTKSEIEGRPETIFQLCCSDSESKTNIVKVIRSILRENFRRHIKCELPLEK TCKDRLVPLKNRVPVSAKLASSRSLKVLKNSSSNEWTGETGKGTLLDSDEGSLSSGTQSSGCPTAEGRQD SKSTSPGKYPHPGLADFADNLIKESDILSDEDDDHRQTVKQGSPTKDIEIQFQRLRISEDPDVHPEAEQQ PGPESGEGQKGGEQPKLVRGHFCPIKRKANSTKRDRGTLLKAQIRHQSLDSQSENATIDLNSVLEREFSV QSLTSVVSEECFYETESHGKS TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_012454 |
ORF Size | 5103 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_012454.2, NM_012454.3, NP_036586.2 |
RefSeq Size | 5916 |
RefSeq ORF | 5106 |
Locus ID | 26230 |
Domains | RhoGEF, PDZ, RBD |
Protein Families | Druggable Genome |
Protein Pathways | Chemokine signaling pathway, Regulation of actin cytoskeleton |
MW | 189.9 kDa |
Gene Summary | This gene encodes a guanine nucleotide exchange factor. A highly similar mouse protein specifically activates ras-related C3 botulinum substrate 1, converting this Rho-like guanosine triphosphatase (GTPase) from a guanosine diphosphate-bound inactive state to a guanosine triphosphate-bound active state. The encoded protein may play a role in neural cell development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] |
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