MAD1 (MAD1L1) (NM_001013836) Human Tagged ORF Clone

CAT#: RC222718L3

Lenti ORF clone of Human MAD1 mitotic arrest deficient-like 1 (yeast) (MAD1L1), transcript variant 2, Myc-DDK-tagged

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: MAD1L1
• Synonyms: MAD1; PIG9; TP53I9; TXBP181
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC222718).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_001013836
• ORF Size: 2154 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001013836.1
• RefSeq Size: 2717
• RefSeq ORF: 2157
• Locus ID: 8379
• Protein Families: Druggable Genome
• Protein Pathways: Cell cycle
• MW: 83.1 kDa
• Gene Summary: MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]