p38 (MAPK14) (NM_139014) Human Tagged ORF Clone
CAT#: RC222774L2
- LentiORF®
Lenti-ORF clone of MAPK14 (mGFP-tagged)-Human mitogen-activated protein kinase 14 (MAPK14), transcript variant 4
"NM_139014" in other vectors (7)
Product Images
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | mGFP |
Symbol | MAPK14 |
Synonyms | CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; p38; p38ALPHA; PRKM14; PRKM15; RK; SAPK2A |
Vector | pLenti-C-mGFP |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC222774).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_139014 |
ORF Size | 921 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers. |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_139014.1, NP_620583.1 |
RefSeq Size | 3679 bp |
RefSeq ORF | 924 bp |
Locus ID | 1432 |
Cytogenetics | 6p21.31 |
Protein Families | Druggable Genome, Protein Kinase |
Protein Pathways | Amyotrophic lateral sclerosis (ALS), Epithelial cell signaling in Helicobacter pylori infection, Fc epsilon RI signaling pathway, GnRH signaling pathway, Leukocyte transendothelial migration, MAPK signaling pathway, Neurotrophin signaling pathway, NOD-like receptor signaling pathway, Progesterone-mediated oocyte maturation, RIG-I-like receptor signaling pathway, T cell receptor signaling pathway, Toll-like receptor signaling pathway, VEGF signaling pathway |
MW | 35.3 kDa |
Gene Summary | 'The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]' |
Documents
Product Manuals |
FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC124170 | MAPK14 (untagged)-Human mitogen-activated protein kinase 14 (MAPK14), transcript variant 4 |
USD 660.00 |
|
SC323402 | MAPK14 (untagged)-Kinase deficient mutant (K53M) of Human mitogen-activated protein kinase 14 (MAPK14), transcript variant 4 |
USD 660.00 |
|
RC222774 | MAPK14 (Myc-DDK-tagged)-Human mitogen-activated protein kinase 14 (MAPK14), transcript variant 4 |
USD 420.00 |
|
RG222774 | MAPK14 (GFP-tagged) - Human mitogen-activated protein kinase 14 (MAPK14), transcript variant 4 |
USD 460.00 |
|
RC222774L1 | Lenti-ORF clone of MAPK14 (Myc-DDK-tagged)-Human mitogen-activated protein kinase 14 (MAPK14), transcript variant 4 |
USD 620.00 |
|
RC222774L3 | Lenti-ORF clone of MAPK14 (Myc-DDK-tagged)-Human mitogen-activated protein kinase 14 (MAPK14), transcript variant 4 |
USD 620.00 |
|
RC222774L4 | Lenti-ORF clone of MAPK14 (mGFP-tagged)-Human mitogen-activated protein kinase 14 (MAPK14), transcript variant 4 |
USD 620.00 |
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