CCR10 (NM_016602) Human Tagged ORF Clone
CAT#: RC222924L1
- LentiORF®
Lenti ORF clone of Human chemokine (C-C motif) receptor 10 (CCR10), Myc-DDK-tagged
"NM_016602" in other vectors (6)
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | CCR10 |
Synonyms | GPR2 |
Vector | pLenti-C-Myc-DDK |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC222924).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_016602 |
ORF Size | 1086 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers. |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_016602.1, NP_057686.1 |
RefSeq Size | 1244 bp |
RefSeq ORF | 1089 bp |
Locus ID | 2826 |
UniProt ID | P46092 |
Cytogenetics | 17q21.2 |
Protein Families | Druggable Genome, GPCR, Transmembrane |
Protein Pathways | Chemokine signaling pathway, Cytokine-cytokine receptor interaction |
MW | 38.2 kDa |
Gene Summary | 'Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27; MIM 604833); CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900]).[supplied by OMIM, Mar 2008]' |
Documents
Product Manuals |
FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC114153 | CCR10 (untagged)-Human chemokine (C-C motif) receptor 10 (CCR10) |
USD 610.00 |
|
RC222924 | CCR10 (Myc-DDK-tagged)-Human chemokine (C-C motif) receptor 10 (CCR10) |
USD 420.00 |
|
RG222924 | CCR10 (GFP-tagged) - Human chemokine (C-C motif) receptor 10 (CCR10) |
USD 460.00 |
|
RC222924L2 | Lenti ORF clone of Human chemokine (C-C motif) receptor 10 (CCR10), mGFP tagged |
USD 620.00 |
|
RC222924L3 | Lenti ORF clone of Human chemokine (C-C motif) receptor 10 (CCR10), Myc-DDK-tagged |
USD 620.00 |
|
RC222924L4 | Lenti ORF clone of Human chemokine (C-C motif) receptor 10 (CCR10), mGFP tagged |
USD 620.00 |
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