DHX36 (NM_020865) Human Tagged ORF Clone

CAT#: RC223929L4

Lenti ORF clone of Human DEAH (Asp-Glu-Ala-His) box polypeptide 36 (DHX36), transcript variant 1, mGFP tagged

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: mGFP
• Symbol: DHX36
• Synonyms: DDX36; G4R1; MLEL1; RHAU
• Vector: pLenti-C-mGFP-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC223929).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_020865
• ORF Size: 3024 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_020865.1, NP_065916.1, NP_065916.2
• RefSeq Size: 3600
• RefSeq ORF: 3027
• Locus ID: 170506
• Domains: DEAD, helicase_C, HA2
• MW: 114.6 kDa
• Gene Summary: This gene is a member of the DEAH-box family of RNA-dependent NTPases which are named after the conserved amino acid sequence Asp-Glu-Ala-His in motif II. The protein encoded by this gene has been shown to enhance the deadenylation and decay of mRNAs with 3'-UTR AU-rich elements (ARE-mRNA). The protein has also been shown to resolve into single strands the highly stable tetramolecular DNA configuration (G4) that can form spontaneously in guanine-rich regions of DNA. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]