CHREBP (MLXIPL) (NM_032954) Human Tagged ORF Clone

CAT#: RC224242L4

Lenti-ORF clone of MLXIPL (mGFP-tagged)-Human MLX interacting protein-like (MLXIPL), transcript variant 4

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: mGFP
• Symbol: MLXIPL
• Synonyms: bHLHd14; CHREBP; MIO; MLX; MONDOB; WBSCR14; WS-bHLH
• Vector: pLenti-C-mGFP-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC224242).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_032954
• ORF Size: 2493 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_032954.2, NP_116572.1
• RefSeq Size: 3225
• RefSeq ORF: 2496
• Locus ID: 51085
• MW: 90.5 kDa
• Gene Summary: This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]