UNC5C (NM_003728) Human Tagged ORF Clone

CAT#: RC224257L3

Lenti ORF clone of Human unc-5 homolog C (C. elegans) (UNC5C), Myc-DDK-tagged

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: UNC5C
• Synonyms: UNC5H3
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC224257).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_003728
• ORF Size: 2793 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_003728.2, NP_003719.2, NP_003719.3
• RefSeq Size: 3646
• RefSeq ORF: 2796
• Locus ID: 8633
• Domains: DEATH, tsp_1, ZU5, ig
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Axon guidance
• MW: 102.9 kDa
• Gene Summary: This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediate the repellent response to netrin; they are transmembrane proteins containing 2 immunoglobulin (Ig)-like domains and 2 type I thrombospondin motifs in the extracellular region. [provided by RefSeq, Jul 2008]