Apc11 (ANAPC11) (NM_001002249) Human Tagged ORF Clone
CAT#: RC224701L4
- LentiORF®
Lenti-ORF clone of ANAPC11 (mGFP-tagged)-Human anaphase promoting complex subunit 11 (ANAPC11), transcript variant 7
"NM_001002249" in other vectors (4)
Product Images
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Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | mGFP |
Symbol | ANAPC11 |
Synonyms | APC11; Apc11p; HSPC214 |
Vector | pLenti-C-mGFP-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC224701).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_001002249 |
ORF Size | 252 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001002249.1, NP_001002249.1 |
RefSeq Size | 977 |
RefSeq ORF | 255 |
Locus ID | 51529 |
Protein Families | Druggable Genome |
Protein Pathways | Cell cycle, Oocyte meiosis, Progesterone-mediated oocyte maturation, Ubiquitin mediated proteolysis |
MW | 9.8 kDa |
Gene Summary | Together with the cullin protein ANAPC2, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex. [UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC300416 | ANAPC11 (untagged)-Human anaphase promoting complex subunit 11 (ANAPC11), transcript variant 7 |
USD 420.00 |
|
RC224701 | ANAPC11 (Myc-DDK-tagged)-Human anaphase promoting complex subunit 11 (ANAPC11), transcript variant 7 |
USD 420.00 |
|
RG224701 | ANAPC11 (GFP-tagged) - Human anaphase promoting complex subunit 11 (ANAPC11), transcript variant 7 |
USD 460.00 |
|
RC224701L3 | Lenti-ORF clone of ANAPC11 (Myc-DDK-tagged)-Human anaphase promoting complex subunit 11 (ANAPC11), transcript variant 7 |
USD 620.00 |
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